| BMC Research Notes | |
| Retrospective survival in elderly COPD patients receiving pulmonary rehabilitation; a study including maintenance rehabilitation | |
| Ulf Aaseboe3  Elisabeth Kristiansen Benum4  Kathrine Meisler Antonsen1  Marijke Jongsma Risberg5  Tormod Brenn2  Audhild Hjalmarsen3  | |
| [1] Department of Pediatry, Central Hospital of Nordland, Bodoe, Norway;Department of Community Medicine, University of Tromsoe, Tromsoe, Norway;Department of Clinical Medicine, University of Tromsoe, Tromsoe N 9038, Norway;Department of Medicine, General Hospital of Helgeland, Sandnessjoen, Sandnessjoen, Norway;Department of Physioterapy, University Hospital of North Norway, Tromsoe, Norway | |
| 关键词: Survival; ltot; Pulmonary rehabilitation; Elderly; Copd; | |
| Others : 1134025 DOI : 10.1186/1756-0500-7-210 |
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| received in 2013-04-19, accepted in 2014-03-21, 发布年份 2014 | |
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【 摘 要 】
Background
The aim of this study was to examine retrospective survival in elderly chronic obstructive pulmonary disease (COPD) patients receiving three different pulmonary rehabilitation (PR) programs.
Results
193 patients [m / f 92 / 101, mean age 69.2 (standard deviation 8.6)] receiving PR were studied with lifetable and Cox regression analyses. Forced expiratory volume in 1 second (FEV1) % pred. was significantly different in the in-patient (n = 72), out-patient (n = 72), and maintenance group (n = 49) [mean 54.5 (21.8), 52.2 (17.7), and 42.9 (15.0), respectively (p = 0.004)]. PR days were 30.3 (20.4), 18.9 (10.4) and 30.0 (20.3), respectively (p < 0.001). Median survival rate was nine years in the in-patient, eight years in the out-patient and seven years in the maintenance group. Hospital stays and days were significantly increased in the maintenance group compared with the other groups (p = 0.003 and 0.010, respectively). The impact of evaluated variables on survival in the three PR groups was significant for age, FEV1 as well as the use of long-term oxygen therapy (LTOT) (HR 1.06, for five years, p < 0.001, HR 0.98, p = 0.01, and HR 2.18, p = 0.005, respectively).
Conclusions
The COPD patients in the maintenance group showed a worse survival, but after correction for gender, age and severity of obstruction, the difference was not statistically significant.
【 授权许可】
2014 Hjalmarsen et al.; licensee BioMed Central Ltd.
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| 20150305051857659.pdf | 341KB | ||
| Figure 2. | 58KB | Image | |
| Figure 1. | 47KB | Image |
【 图 表 】
Figure 1.
Figure 2.
【 参考文献 】
- [1]Fletcher C, Peto R, Tinker C, Speizer FE: The natural history of chronic bronchitis and emphysema. Oxford: Oxford University Press; 1976.
- [2]ACCP-AACVPR: Pulmonary Rehabilitation Guidelines Panel. Pulmonary rehabilitation: joint ACCP/AACVPR evidence based guidelines. Chest 1997, 112:1363-1396.
- [3]Nici L, Donner C, Wouters E, Zuwallack R, Ambrosino N, Bourbeau J, Carone M, Celli B, Engelen M, Fahy B, Garvey C, Goldstein R, Gosselink R, Lareau S, MacIntyre N, Maltais F, Morgan M, O’Donnell D, Prefault C, Reardon J, Rochester C, Schols A, Singh S, Troosters T: American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation. ATS/ERS Pulmonary Rehabilitation Writing Committee. Am J Respir Crit Care Med 2006, 173:1390-1413.
- [4]Verrill D, Barton C, Beasley W, Lippard WM: The effects of short-term and long-term pulmonary rehabilitation on functional capacity, perceived dyspnea, and quality of life. Chest 2005, 128:673-683.
- [5]Guyatt GH, Sullivan MJ, Thompson PJ, Fallen EL, Pugsley SO, Taylor DW, Berman LB: The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure. Can Med Assoc J 1985, 132:919-923.
- [6]Borg GA: Psychophysical bases of perceived exertion. Med Sci Sports Exerc 1982, 14:377-381.
- [7]Jones P, Quirk F, Baveystock C, Littlejohns P: A self-complete measure of health status for chronic airflow limitation: the St. George’s Respiratory Questionnaire. Am Rev Respir Dis 1992, 145:1321-1327.
- [8]Casaburi R, Porszasz J, Burns MR, Carithers ER, Chang RS, Cooper CB: Physiologic benefits of exercise training in rehabilitation of patients with severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1997, 155:1541-1551.
- [9]Troosters T, Gosselink R, Decramer M: Short- and long-term effects of outpatient rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Am J Med 2000, 109:207-212.
- [10]Hodgkin JE: Pulmonary rehabilitation: history and definition. In Pulmonary Rehabilitation, Guidelines to Success. 4th edition. Edited by Hodgkin JE, Celli BR, Connors GL. USA: Mosby Elsevier; 2009:1-7.
- [11]ZuWallack R: Outcome assessment. In Pulmonary Rehabilitation, Guidelines to Success. 4th edition. Edited by Hodgkin JE, Celli BR, Connors GL. USA: Mosby Elsevier; 2009:330-350.
- [12]Lacasse Y, Wong E, Guyatt GH, King D, Cook DJ, Goldstein RS: Metaanalysis of respiratory rehabilitation in chronic obstructive pulmonary disease. Lancet 1996, 348:1115-1119.
- [13]Griffiths TL, Burr ML, Campbell IA, Lewis-Jenkins V, Mullins J, Shiels K, Turner-Lawlor PJ, Payne N, Newcombe RG, Ionescu AA, Thomas J, Tunbridge J: Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomized controlled trial. Lancet 2000, 355:362-368.
- [14]Ries AL, Kaplan RM, Limberg TM, Prewitt LM: Effects of pulmonary rehabilitation on physiologic and psychosocial outcomes in patients with chronic obstructive pulmonary disease. Ann Intern Med 1995, 122:823-832.
- [15]Bourbeau J, Julien M, Maltais F, Rouleau M, Beaupré A, Bégin R, Renzi P, Nault D, Borycki E, Schwartzman K, Singh R, Collet JP: Reduction of hospital utilization in patients with chronic obstructive pulmonary disease: a disease-specific self-management intervention. Arch Intern Med 2003, 163:585-591.
- [16]Californian Pulmonary Rehabilitation Collaborative Group: Effects of pulmonary rehabilitation on dypnea, quality of life, and healthcare costs in California. J Cardiopulm Rehabil 2004, 24:52-62.
- [17]Raskin J, Spiegler P, McCusker C, ZuWallack R, Bernstein M, Busby J, DiLauro P, Griffiths K, Haggerty M, Hovey L, McEvoy D, Reardon JZ, Stavrolakes K, Stockdale-Woolley R, Thompson P, Trimmer G, Youngson L: The effects of pulmonary rehabilitation on healthcare utilization in chronic obstructive pulmonary disease: the Northeast Pulmonary Rehabilitation Consortium. J Cardiopulm Rehabil 2006, 26:231-236.
- [18]Beauchamp MK, Evans R, Janaudis-Ferreira T, Goldstein RS, Brooks D: Systematic review of supervised exercise programs after pulmonary rehabilitation in individuals with COPD. Chest 2013, 144:1124-1133.
- [19]Global Initiative for Chronic Obstructive Lung Diseases In NHLBI/WHO workshop report. Bethesda: National Institutes of Health; 2001:1-100. Updated 2013 at http://www.goldcopd.org webcite
- [20]Spruit MA: Maintenance programs after pulmonary rehabilitation. How may we advance this field? Chest 2013, 144:1091-1193.
- [21]Nocturnal Oxygen Therapy Trial Group: Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease. Ann Intern Med 1980, 93:391-398.
- [22]Medical Research Council Working Party: Long-term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Lancet 1981, 1:681-686.
- [23]Hjalmarsen A, Melbye H, Wilsgaard T, Holmboe JH, Opdahl R, Viitanen M: Prognosis for chronic obstructive pulmonary disease patients who receive long-term oxygen therapy. Int J Tuberc Lung Dis 1999, 3:1120-1126.
- [24]Dr C: Regression models and life Tables. J R Statist Soc B 1972, 34:187-220.
- [25]Celli BR, Cote CG, Marin JM, Casanova C, Montes De Oca M, Mendez RA, Pinto Plata V, Cabral HJ: The body-mass-index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med 2004, 350:1005-1012.
- [26]Seemungal T, Hurst JR, Wedzicha JA: Exacerbation rate, health status and mortality in COPD – a review of potential interventions. Int J COPD 2009, 4:203-223.
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