Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial

BMC Psychiatry

Patrick Callaghan⁵  Marie Armstrong³  Emily Brighton⁵  Elizabeth Khalil⁵  Ioannis Morres⁴  David Turner¹  Boliang Guo²  Tim Carter⁵ 

[1] School of Medicine, University of East Anglia, East Anglia, UK;Division of Psychiatry & Applied Psychology, University of Nottingham, Nottingham, UK;Specialist CAMHS, Nottinghamshire Healthcare NHS Trust, Nottingham, UK;Department of Physical Education & Sport Science, University of Thessaly, Trikala, Greece;School of Health Sciences, University of Nottingham, Nottingham, UK

关键词: RCT;    Physical activity;    Exercise;    Young people;    Adolescence;    Depression;   

Others  :  1231610
DOI  :  10.1186/s12888-015-0638-z

 received in 2015-01-30, accepted in 2015-10-06,  发布年份 2015

【 摘 要 】

Background

Exercise has been shown to be effective in treating depression, but trials testing the effect of exercise for depressed adolescents utilising mental health services are rare. The aim of this study was to determine the effectiveness of a preferred intensity exercise intervention on the depressive symptoms of adolescents with depression.

Methods

We randomly assigned 87 adolescents who were receiving treatment for depression to either 12 sessions of aerobic exercise at preferred intensity alongside treatment as usual or treatment as usual only. The primary outcome was depressive symptom change using the Children’s Depression Inventory 2 ^ndVersion (CDI-2) at post intervention. Secondary outcomes were health-related quality of life and physical activity rates. Outcomes were taken at baseline, post intervention and at six month follow up.

Results

CDI-2 score reduction did not differ significantly between groups at post-intervention (est. 95 % CI −6.82, 1.68, p = 0.23). However, there was a difference in CDI-2 score reduction at six month follow-up in favour of the intervention of −4.81 (est. 95 % CI −9.49, −0.12, p = 0.03). Health-related quality of life and physical activity rates did not differ significantly between groups at post-intervention and follow-up.

Conclusions

There was no additional effect of preferred intensity exercise alongside treatment as usual on depressive reduction immediately post intervention. However, effects were observed at six months post-intervention, suggesting a delayed response. However, further trials, with larger samples are required to determine the validity of this finding.

Trial registration

ClinicalTrials.gov NCT01474837, March 16 2011

【 授权许可】

   
2015 Carter et al.

【 图 表 】

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