HOPE-trial: hemiarthroplasty compared to total hip arthroplasty for displaced femoral neck fractures in the elderly-elderly, a randomized controlled trial

BMC Musculoskeletal Disorders

Mats Salemyr¹  Carl-Johan Hedbeck¹  Hans Nåsell¹  Olle Muren¹  Sebastian Mukka²  Ghazi Chammout¹  Olof Sköldenberg¹ 

[1]Department of Clinical Sciences, Division of Orthopaedics, Karolinska Institutet at Danderyd Hospital, Danderyd, S-182 88, Sweden

[2]Department of Surgical and Perioperative Science, Umeå University, Umeå, S-901 85, Sweden

关键词: Octagenerians;    Randomized clinical trial;    Harris hip score;    Total hip arthroplasty;    Hemiarthroplasty;    Femoral neck fracture;   

Others  :  1232814
DOI  :  10.1186/s12891-015-0763-3

 received in 2015-04-20, accepted in 2015-10-08,  发布年份 2015

【 摘 要 】

Background

A femoral neck fracture (FNF) is a common cause of suffering and premature death in the elderly population. Optimizing the treatment for improved outcome and a reduced need for secondary surgery is important both for the patient and the society. The choice of primary total or hemiarthroplasty in patients over eighty years are controversial. We hypothesized that total hip arthroplasty has an equal or better outcome in patient-reported outcome compared with hemiarthroplasty.

Methods/Design

A prospective, randomized, single-blinded trial will be conducted. We will include 120 patients, 80 years of age and over with an acute (<36 h) displaced femoral neck fracture. The patients will be randomized in a 1:1 ratio to either total hip arthroplasty or hemiarthroplasty. The primary endpoints are Harris hip Score and EQ-5D. Secondary endpoints include pain measured with visual analogue scale, surgical time, reoperations, complications and radiological measurement of erosion in patients operated with hemiarthroplasty. Follow-up will be performed postoperatively after three months, 1, 2, 4 and 10 years.

Discussion

To our knowledge, this is the first randomized controlled trial comparing total hip arthroplasty and hemiarthroplasty for displaced femoral neck fracture in patients age 80 years and over.

Trial registration

Clinicaltrial.gov: NCT02246335

【 授权许可】

   
2015 Sköldenberg et al.

【 图 表 】

Fig. 1.

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