Outcomes of polytrauma patients with diabetes mellitus

BMC Medicine

Peter V Giannoudis²  Rozalia Dimitriou¹  Omar Bouamra³  Tom Jenks³  Antoinette Edwards³  Fiona Lecky³  James Tebby¹ 

[1] Academic Department of Trauma & Orthopaedic Surgery, University of Leeds, Clarendon Wing, Floor A, Great George Street, Leeds General Infirmary, LS1 3EX Leeds, UK;LIRMM, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, LS7 4SA Leeds, West Yorkshire, Leeds, UK;Trauma Audit and Research Network, 3rd Floor Mayo Building, Salford Royal NHS Foundation Trust, Salford M6 8HD, UK

关键词: Trauma Audit and Research Network;    TARN;    Diabetes mellitus;    Trauma;    Polytrauma;   

Others  :  1123223
DOI  :  10.1186/1741-7015-12-111

 received in 2013-12-12, accepted in 2014-06-06,  发布年份 2014

【 摘 要 】

Background

The impact of diabetes mellitus in patients with multiple system injuries remains obscure. This study was designed to increase knowledge of outcomes of polytrauma in patients who have diabetes mellitus.

Methods

Data from the Trauma Audit and Research Network was used to identify patients who had suffered polytrauma during 2003 to 2011. These patients were filtered to those with known outcomes, then separated into those with diabetes, those known to have other co-morbidities but not diabetes and those known not to have any co-morbidities or diabetes. The data were analyzed to establish if patients with diabetes had differing outcomes associated with their diabetes versus the other groups.

Results

In total, 222 patients had diabetes, 2,558 had no past medical co-morbidities (PMC), 2,709 had PMC but no diabetes. The diabetic group of patients was found to be older than the other groups (P <0.05). A higher mortality rate was found in the diabetic group compared to the non-PMC group (32.4% versus 12.9%), P <0.05). Rates of many complications including renal failure, myocardial infarction, acute respiratory distress syndrome, pulmonary embolism and deep vein thrombosis were all found to be higher in the diabetic group.

Conclusions

Close monitoring of diabetic patients may result in improved outcomes. Tighter glycemic control and earlier intervention for complications may reduce mortality and morbidity.

【 授权许可】

   
2014 Tebby et al.; licensee BioMed Central Ltd.

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