Prevalence of a marker of active helicobacter pylori infection among patients with type 2 diabetes mellitus in Lagos, Nigeria

BMC Research Notes

Olufemi Fasanmade¹  Stella Smith³  Ebere Anomneze²  Aderemi Oluyemi⁴ 

[1] Department of Medicine, Lagos University Teaching Hospital, Idi-Araba, Lagos State, Nigeria;Health Gates Consultancy and Medical Services, Ojuelegba, Lagos State, Nigeria;Division of Molecular Biology, Nigerian Institute of Medical Research, Lagos State, Nigeria;General Hospital, Ikorodu, Lagos State, Nigeria

关键词: Nigeria;    Diabetes mellitus;    Stool antigen test;    Helicobacter pylori infection;   

Others  :  1166330
DOI  :  10.1186/1756-0500-5-284

 received in 2011-11-18, accepted in 2012-06-01,  发布年份 2012

【 摘 要 】

Background

There appears to exist a potentially important interplay between diabetes mellitus (DM) and Helicobacter pylori (H. pylori) infection. Findings from previous studies have been conflicting. Only a few studies have examined the topic in a sub-Saharan African population. This study sought to determine the prevalence of H. pylori infection among Type 2 diabetes mellitus (T2DM) patients in Lagos, Nigeria.

Findings

H. pylori infection was detected in 18% of T2DM patients and 13% of controls but there was no statistical significance in this difference (p = 0.52). The prevalence of H. pylori was neither associated with the known duration of T2DM nor was it associated with age, gender, body mass index (BMI), smoking status. T2DM was not shown to be a risk factor independently associated with risk for H. pylori infection (OR = 0.87, 95% CI = 0.58-1.31, p = 0.57).

Conclusions

The lack of a statistical significant difference between the H. pylori infection rates in T2DM patients and controls suggests that the infection is not increased in T2DM. Larger studies need to be conducted to confirm the study findings.

【 授权许可】

   
2012 Oluyemi et al.; licensee BioMed Central Ltd.

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