Additional perspectives on chronic kidney disease of unknown aetiology (CKDu) in Sri Lanka – lessons learned from the WHO CKDu population prevalence study

BMC Nephrology

Keith E Levine³  James H Raymer³  Kristin Smith²  Joseph Lunyera⁴  Roshini J Peiris-John⁶  Kamani P Wanigasuriya⁵  Rajitha Wickremashinghe¹  Donna S Womack²  Myles F Elledge³  Jennifer Hoponick Redmon² 

[1] Department of Public Health, University of Kelaniya, Kelaniya, Sri Lanka;RTI International, Center for Health and Environmetnal Modeling, 3040 East Cornwallis Rd, Research Triangle Park, NC 27709-2194, USA;RTI International, Discovery Science Technology, 3040 East Cornwallis Rd, Research Triangle Park, NC 27709-2194, USA;Duke University, Global Health Institute, Durham, NC, USA;Department of Medicine, University of Sri Jayewardenepura, Nugegoda, Sri Lanka;University of Auckland Epidemiology & Biostatistics Auckland, New Zealand

关键词: Cadmium;    Agrochemicals;    Heavy metals;    Sri Lanka;    Environmental nephrotoxins;    Chronic kidney disease of unknown aetiology;    Chronic kidney disease;   

Others  :  1082648
DOI  :  10.1186/1471-2369-15-125

 received in 2014-02-11, accepted in 2014-07-16,  发布年份 2014

【 摘 要 】

The recent emergence of an apparently new form of chronic kidney disease of unknown aetiology (CKDu) has become a serious public health crisis in Sri Lanka. CKDu is slowly progressive, irreversible, and asymptomatic until late stages, and is not attributable to hypertension, diabetes, or other known aetiologies. In response to the scope and severity of the emerging CKDu health crisis, the Sri Lanka Ministry of Health and the World Health Organization initiated a collaborative research project from 2009 through 2012 to investigate CKDu prevalence and aetiology. The objective of this paper is to discuss the recently published findings of this investigation and present additional considerations and recommendations that may enhance subsequent investigations designed to identify and understand CKDu risk factors in Sri Lanka or other countries.

【 授权许可】

   
2014 Redmon et al.; licensee BioMed Central Ltd.

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