Identifying persons at risk for developing type 2 diabetes in a concentrated population of high risk ethnicities in Canada using a risk assessment questionnaire and point-of-care capillary blood HbA1c measurement

BMC Public Health

Veronica K Jamnik²  Norman Gledhill³  Michael A Rotondi⁵  Michael C Riddell¹  Lisa A Miadovnik⁴  Chip P Rowan⁴ 

[1] 347 Norman Bethune College, York University, 4700 Keele St., Toronto, Ontario M3J 1P3, Canada;355 Norman Bethune College, York University, 4700 Keele St., Toronto, Ontario M3J 1P3, Canada;356 Norman Bethune College, York University, 4700 Keele St., Toronto, Ontario M3J 1P3, Canada;358 Norman Bethune College, York University, 4700 Keele St., Toronto, Ontario M3J 1P3, Canada;364 Norman Bethune College, York University, 4700 Keele St., Toronto, Ontario M3J 1P3, Canada

关键词: Point of care;    Body mass index;    Physical activity;    Screening;    (Up to 10) pre diabetes;   

Others  :  1127966
DOI  :  10.1186/1471-2458-14-929

 received in 2014-01-29, accepted in 2014-09-02,  发布年份 2014

【 摘 要 】

Background

Amidst the growing health care burden created by diabetes, this study aimed to assess the utility of a prediabetes/type 2 diabetes risk questionnaire in high risk ethnic communities in Toronto Canada.

Methods

Participants (n = 691) provided questionnaire responses and capillary blood tests collected via fingerstick and results were analysed for HbA_1c using the Bio-Rad in2it point-of-care device. The Bland-Altman method was used to compare point-of-care HbA_1c analysis (Bio-Rad, boronate affinity chromatography) to that using high performance liquid chromatography. ANOVA and linear regression were performed to investigate the relationship between questionnaire and blood data.

Results

Mean (±SD) HbA_1c was 5.99% ± 0.84 and the Bland-Altman analysis revealed no significant biases HbA_1c (bias = 0.039, 95% limits of agreement = -1.14 to 1.22). ANOVA showed that with increasing risk classification based on questionnaire answers (with the exception of "moderate"-to-"high"), there was a significant increase in mean HbA_1c (Welch Statistic 30.449, p < 0.001). Linear regression revealed that the number of high risk parents, age category, BMI, physical activity participation and previous diagnosis of high blood sugar were significant contributors (p < 0.05) to the variance in HbA_1c.

Conclusions

Though not a substitute for established diagnostic protocols, the use of a risk questionnaire can be an accurate, low cost, educational and time efficient method for assessment of type 2 diabetes risk. The early detection of prediabetes and type 2 diabetes is vital to increased awareness and opportunity for intervention with the goal of preventing or delaying the progression of type 2 diabetes and the known associated complications.

【 授权许可】

   
2014 Rowan et al.; licensee BioMed Central Ltd.

【 图 表 】

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