Bronchopneumonia in wild boar (Sus scrofa) caused by Rhodococcus equi carrying the VapB type 8 plasmid

BMC Research Notes

Shinji Takai⁵  Gustavo Henrique Batista Lara¹  Márcio Garcia Ribeiro¹  Roselene Ecco⁴  Mateus Matiuzzi da Costa⁶  Andrea Maria Lazzari³  Sônia de Avila Botton²  Letícia Trevisan Gressler²  Fernanda Monego⁷  Agueda Castagna de Vargas² 

[1] Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Sciences, Universidade Estadual Paulista - UNESP, Box 560, Botucatu, State of Sao Paulo, Code 18618-970, Brazil;Department of Preventive Veterinary Medicine, Universidade Federal de Santa Maria, UFSM, 97105-900, Santa Maria, State of Rio Grande do Sul, Brazil;Department of Veterinary Medicine, União Pioneira de Integração Social – UPIS, Brasília, Brazil;Department of Veterinary Clinic and Cirugic, School of Veterinary, Universidade Federal de Minas Gerais -UFMG, State of Minas Gerais, Brazil;Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Kitasato, Japan;Department of Veterinary Medicine, Universidade Federal do Vale do São Francisco - UNIVASF, Petrolina, State of Pernambuco, Brazil;Department of Microbiology, Universidade do Contestado- UnC, Santa Catarina, Brazil

关键词: Bronchopneumonia;    VapB plasmid;    Wild boar (Sus scrofa);    Rhodococcus equi;   

Others  :  1143152
DOI  :  10.1186/1756-0500-6-111

 received in 2012-11-09, accepted in 2013-03-18,  发布年份 2013

【 摘 要 】

Background

Rhodococcus equi is associated with pyogranulomatous infections, especially in foals, and this bacterium has also emerged as a pathogen for humans, particularly immunocompromised patients. R. equi infections in pigs, wild boar (Sus scrofa) and humans are mainly due to strains carrying the intermediate virulence (VapB) plasmid. In Brazil, R. equi carrying the VapB type 8 plasmid is the most common type recovered from humans co-infected with the human immunodeficiency virus (HIV). R. equi infection in pigs and wild boar is restricted predominantly to the lymphatic system, without any reports of pulmonary manifestations.

Findings

This report describes the microbiological and histopathological findings, and molecular characterization of R. equi in two bronchopneumonia cases in wild boar using PCR and plasmid profile analysis by digestion with restriction endonucleases. The histological findings were suggestive of pyogranulomatous infection, and the plasmid profile of both R. equi isolates enabled the characterization of the strains as VapB type 8.

Conclusions

This is the first report of bronchopneumonia in wild boar due to R. equi. The detection of the VapB type 8 plasmid in R. equi isolates emphasize that wild boar may be a potential source of pathogenic R. equi strains for humans.

【 授权许可】

   
2013 de Vargas et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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