Cyclospora infection in a young woman with human immunodeficiency virus in Hong Kong: a case report

BMC Research Notes

Wai-shing Leung¹  Kay-yan Tsang¹  Jacky Man-chun Chan¹  Bosco Hoi-shiu Lam²  Richard Wing-cheuk Wong²  Owen Tak-yin Tsang¹ 

[1] Hospital Authority Infectious Disease Centre at Princess Margaret Hospital, 2-10 Princess Rm 313, Blk S, Margaret Hospital Rd, Lai Chi Kok, Hong Kong, SAR, China;Department of Pathology, Princess Margaret Hospital, Hong Kong, China

关键词: Prolonged diarrhoea;    HIV;    Protozoa;    Cyclospora;   

Others  :  1140536
DOI  :  10.1186/1756-0500-6-521

 received in 2013-07-04, accepted in 2013-12-04,  发布年份 2013

【 摘 要 】

Background

Cyclospora is an uncommon pathogen. The diagnosis of Cyclospora infection can be difficult because of its scarcity in developed countries, intracellular mode of life, small size of the parasite and its inability to take up routine microscopic stains. However, it is endemic in many countries in Asia, Africa, Central and South America. With the increase in travels to these areas, the number of cases is expected to increase. Moreover, it is found to be associated with numerous food-borne outbreaks.

Case presentation

We encountered a patient with human immunodeficiency virus presented with 6 months of diarrhoea. The initial investigation was unrevealing. The diagnosis of Cyclospora infection was finally made on the histological sample obtained by colonoscopy. Moreover, the initial therapy with ciprofloxacin was not effective, while trimethoprim/sulfamethoxazole resulted in final cure of the disease.

Conclusion

Travel and food histories are important for the suspicion of Cyclospora infection. Histological examination is more sensitive in making a diagnosis of Cyclospora infection of the gut than fecal microscopic examination. Trimethoprim/sulfamethoxazole is a more reliable therapy for Cyclospora infection in patients with human immunodeficiency virus.

【 授权许可】

   
2013 Tsang et al.; licensee BioMed Central Ltd.

【 图 表 】

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