BMC Infectious Diseases | |
Rubella seroprevalence among pregnant women in Burkina Faso | |
Jean B Ouedraogo3  Claude P Muller2  Jacques R Kremer2  Emilie Charpentier2  Da Ernest1  Zekiba Tarnagda3  Judith M Hübschen2  Marc C Tahita3  | |
[1] Clinique Lorentia, Ministère de la Santé, Bobo-Dioulasso, 01 BP 502, Burkina Faso;Institute of Immunology, Centre de Recherche Public de la Santé/Laboratoire National de Santé, 20A rue Auguste Lumière, Luxembourg, L, 1950, Luxembourg;Institut de Recherche en Sciences de la Santé, 399 Avenue de la liberté, Bobo-Dioulasso, BP 545, Burkina Faso | |
关键词: Burkina Faso; IgG; Seroprevalence; Rubella; | |
Others : 1149037 DOI : 10.1186/1471-2334-13-164 |
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received in 2012-12-17, accepted in 2013-03-26, 发布年份 2013 | |
【 摘 要 】
Background
Despite the serious consequences of rubella infection during early pregnancy, very little is known about the rubella seroprevalence in a number of African countries including Burkina Faso.
Methods
Between December 2007 and March 2008 serum samples were collected from 341 pregnant women in Bobo (n = 132, urban area) and Houndé (n = 209, rural area) and were tested for rubella-specific IgG antibodies with a commercial ELISA kit.
Results
An overall seropositivity rate of 95.0% (324/341) was found, with a higher percentage in the urban population and in the oldest age group. Considering an antibody titer of at least 10 International Units per ml as protective, the overall immunity rate in the cohort of pregnant women was 93.3% (318/341).
Conclusions
The high overall seropositivity rate in the absence of routine immunization suggests a continuous transmission of endemic rubella virus in Burkina Faso, posing a threat to non-immune pregnant women.
【 授权许可】
2013 Tahita et al.; licensee BioMed Central Ltd.
【 预 览 】
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20150405011446131.pdf | 138KB | download |
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