Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection

BMC Medical Imaging

Burckhardt Ringe¹  Frank Wacker³  Eva-Doreen Pfister⁵  Thomas Becker⁴  Hoen-oh Shin³  Christian von Falck³  Bastian Paul Ringe²  Kristina Imeen Ringe³ 

[1] Drexel University, College of Medicine, 216 N Broad Street, Philadelphia, PA, 19102, USA;Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Carl-Neuberg Str.1, 30625, Hannover, Germany;Department of Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany;Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, Arnold-Heller Str.1, 24105, Kiel, Germany;Department of Pediatric Gastroenterology and Hepatology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany

关键词: CT;    Recipient;    Living donor;    Transplantation;    LDLT;   

Others  :  1091945
DOI  :  10.1186/1471-2342-12-21

 received in 2012-03-12, accepted in 2012-07-24,  发布年份 2012

【 摘 要 】

Background

Living donor liver transplantation (LDLT) is a valuable and legitimate treatment for patients with end-stage liver disease. Computed tomography (CT) has proven to be an important tool in the process of donor evaluation. The purpose of this study was to evaluate the significance of CT in the donor selection process.

Methods

Between May 1999 and October 2010 170 candidate donors underwent biphasic CT. We retrospectively reviewed the results of the CT and liver volumetry, and assessed reasons for rejection.

Results

89 candidates underwent partial liver resection (52.4%). Based on the results of liver CT and volumetry 22 candidates were excluded as donors (31% of the cases). Reasons included fatty liver (n = 9), vascular anatomical variants (n = 4), incidental finding of hemangioma and focal nodular hyperplasia (n = 1) and small (n = 5) or large for size (n = 5) graft volume.

Conclusion

CT based imaging of the liver in combination with dedicated software plays a key role in the process of evaluation of candidates for LDLT. It may account for up to 1/3 of the contraindications for LDLT.

【 授权许可】

   
2012 Ringe et al.; licensee BioMed Central Ltd.

【 图 表 】

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