Capsule colonoscopy increases uptake of colorectal cancer screening

BMC Gastroenterology

Thomas Rösch¹  Lutz Altenhofen²  Jürgen Ferdinand Riemann²  Ulrich Gauger²  Friedrich Schütte²  Nora Plathner²  Murat Bastürk²  Michael Börner²  Helge Hill²  Rainer Behrendt²  Horst Krause²  Stefan Groth² 

[1]Department of Interdisciplinary Endoscopy, University Hospital Hamburg Eppendorf, Martinistr. 52, 20246, Hamburg, Germany

[2]Private Gastroenterology Offices Rinteln, BKK 24 Medical Insurance, Obernkirchen, LebensBlicke Foundation for the Prevention of Colon Cancer, Ludwigshafen, Central Research Institute of Ambulatory Health Care, Berlin, Germany

关键词: Patient acceptability;    Capsule colonoscopy;    Uptake;    Screening colonoscopy;   

Others  :  1113017
DOI  :  10.1186/1471-230X-12-80

 received in 2012-02-10, accepted in 2012-06-26,  发布年份 2012

【 摘 要 】

Background

Screening colonoscopy effectiveness is hampered by limited adherence by the general population. The present prospective study was performed to evaluate whether adding capsule colonoscopy to the endoscopic screening options increases uptake.

Methods

Invitation letters were sent to 2150 persons above the age of 55 insured with a German medical insurance company in the area of Rinteln, Lower Saxony with a baseline spontaneous annual screening colonoscopy uptake of 1 %. Both capsule or conventional colonoscopy were offered. Interested persons were given information about the two screening options by four local gastroenterologists and examinations were then performed according to screenees’ final choice.

Results

154 persons sought further information, and 34 and 90 underwent conventional and capsule colonoscopy, respectively. Colonoscopy uptake was thus increased by the invitation process by 60 % (1.6 % vs. 1 %; p = 0.075), while the option of capsule endoscopy led to a fourfold increase of screening uptake (4.2 % vs. 1 %, p < 0.001). Despite similar age distribution in both sex groups, uptake in men was significantly higher (5.6 % vs. 2.8 %, p = 002). However, overall adenoma yield was not different in both groups.

Conclusions

The present study suggests that offering the option of capsule colonoscopy increases uptake of endoscopic colorectal cancer screening. However, capsule endoscopy sensitivity for adenoma detection needs to be improved.

【 授权许可】

   
2012 Groth et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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