Public health implications of contamination of Franc CFA (XAF) circulating in Buea (Cameroon) with drug resistant pathogens

BMC Research Notes

Theresa K Nkuo-Akenji²  Henry Meriki Dilonga²  Nana Gaelle²  Jane-Francis Tatah Kihla Akoachere¹ 

[1]Laboratory for Emerging Infectious Diseases, Faculty of Science, University of Buea, Buea, Cameroon

[2]Department of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon

关键词: Cameroon;    Fungi;    Bacteria;    Resistance;    Susceptibility;    Antibiotics;    Pathogens;    Contamination;    Franc CFA (XAF);    Currency;   

Others  :  1134934
DOI  :  10.1186/1756-0500-7-16

 received in 2013-12-21, accepted in 2014-01-03,  发布年份 2014

【 摘 要 】

Background

Studies in different parts of the world have implicated money as a vehicle for transmission of pathogens. Such information which is necessary to facilitate infection control strategies is lacking in many sub-Saharan countries including Cameroon. This study analyzed the Franc de la Communauté Financiere d’Afrique (Franc CFA), the currency used in Cameroon and other countries in the Central African sub-region, as a potential vehicle for transmission of pathogenic bacteria and fungi, particularly drug-resistant strains, to generate findings which could create awareness on currency contamination and serve as a guide when formulating health policies on currency.

Methods

Two hundred and thirteen currency samples representing various denominations of notes and coins randomly collected from diverse sources in Buea, Cameroon were analyzed for bacteria and fungi. The sensitivity of bacterial isolates to antibiotics was tested using the disc diffusion method. The relationship between contamination and physical state, source or denomination of currency was assessed using the χ² test. All statistics were discussed at 0.05 significance level.

Results

Two hundred (93.9%) samples were contaminated with notes (96.6%) showing higher contamination than coins (88.2%). Uncirculated (mint) samples showed no contamination. There was a significant difference (P˂0.05) in contamination with respect to currency denomination, physical state and source. All samples from butchers and patients/personnel in hospitals were contaminated. Lower denominations showed significantly higher (P = 0.008) levels of contamination than higher denominations. Dirty currency was more contaminated than clean currency. Nine bacterial species were isolated. Coagulase-negative Staphylococcus (CoNS) (54.9%) and Staphylococcus aureus (20.1%) predominated. Among the fungi detected, Aspergillus sp (17.3%) and Penicillium sp (15.9%) showed higher frequency of occurrence. Bacteria were susceptible (100%) to ceftriaxone, gentamicin, norfloxacin and ofloxacin. Susceptibility to amoxicillin, penicillin, ampicillin, vancomycin and cotrimoxazole was low. Staphylococci were resistant (100%) to vancomycin, penicillin G, and amoxicillin. CoNS in addition showed resistance (100%) to cotrimoxazole.

Conclusions

The CFA franc circulating in Buea could serve as a vehicle for transmission of drug resistant pathogenic or potential organisms and contamination could be due to currency usage and handling as mint notes were not contaminated. Hygiene practices during or after handling currency is greatly encouraged to prevent infection.

【 授权许可】

   
2014 Akoachere et al.; licensee BioMed Central Ltd.

【 参考文献 】

• [1]Anderson RM, May RM: Infectious Diseases of Humans, Dynamics and Control. New York: Oxford University Press; 1992.
• [2]Cooper E: Intestinal parasitoses and the modern description of diseases of poverty. T Roy Soc Trop Med H 1991, 85:168-170.
• [3]Jenkins AJ: Drug contamination of US paper currency. Forensic Sci Int 2001, 121:189-193.
• [4]Lavins ES, Lavins BD, Jenkins AJ: Cannabis (Marijuana) contamination of United States and foreign paper currency. J Anal Toxicol 2004, 28:439-442.
• [5]Jourdan TH, Veitenheimer AM, Murray CK, Wagner JR: The quantitation of cocaine on US currency: a survey and significance of the levels of contamination. J Forensic Sci 2013, 58(3):616-624. doi:10.1111/1556-4029.12097
• [6]News DJ: Add to the evils of money the fact it carries many germs http://www.foodcontamination.ca/fsnet/1998/1-1998/fs-01-26-98-01.txt webcite
• [7]Abrams BL, Waterman NG: Dirty money. J Am Med Assoc 1972, 219:1202-1212.
• [8]Kuria JKN, Wahone RG, Kariuki SM: Profile of bacteria and fungi on money coins. E Afr Med J 2009, 86:151-155.
• [9]World Health Organization (WHO): Foodborne safety and foodborne illnesses. Fact Sheet 237:7. http://www.who.int/infectious-disease-report/2002/.2000 webcite
• [10]Jiang X, Doyle MP: Fate of Escherichia coli O157:H7 and Salmonella enteritidis on currency. J Food Protect 1999, 62:805-807.
• [11]Michaels B: Money and serving ready-to-eat food. Food Serv Technol 2002, 2:1-3.
• [12]Pope TM, Ender PT, Woelk WK, Koroscil MA, Koroscil TM: Bacterial contamination of paper currency. South Med J 2002, 95:1408-1410.
• [13]Khin NO, Phyu PW, Aung MH, Aye T: Contamination of currency notes with enteric bacterial pathogens. J Diarrhoeal Dis Res 1989, 7:92-94.
• [14]Uneke CJ, Ogbu O: Potential for parasite and bacterial transmission by paper currency in Nigeria. J Environ Health 2007, 69:54-60.
• [15]Yazah AJ, Yusuf J, Agbo AJ: Bacterial contamination of Nigerian currency notes and associated risk factors. Res J Med Sci 2012, 6:1-6.
• [16]Ngwai YB, Ezenwa FC, Ngadda N: Contamination of Nigerian currency notes by Escherichia coli in Nasarawa State University, Keffi. Nigeria Asian J Pharmaceut Health Sci 2011, 1(4):164-166.
• [17]Kawo AH, Adam MS, Abdullahi BA, Sani NM: Prevalence and public health implications of the microbial load of abused naira notes. Bajopas 2009, 2(1):52-57.
• [18]Ehwarieme DA: R-plasmids amongst Escherichia coli 0157:H7 isolated from Nigerian currency notes. Afr J Microbiol Res 2012, 6:1966-1969.
• [19]Igumbor EO, Obi CL, Bessong PO, Potgieter N, Mkasi TC: Microbiological analysis of banknotes circulating in the Venda region of Limpopo province, South Africa. S Afr J Sci 2007, 103:365-366.
• [20]Tagoe DNA, Adams L, Kangah VG: Antibiotic resistant bacterial contamination of the Ghanaian currency note: a potential health problem. J Microbiol Biotech Res 2011, 1:37-44.
• [21]Kumar JD, Negi YK, Khanna D: Detection of virulence genes in Staphylococcus aureus isolated from paper currency. Int J Infect Dis 2009, 13:450-455.
• [22]Oyero OG, Emikpe BO: Preliminary investigation on the microbial contamination of Nigerian currency. Int J Trop Med 2007, 2:29-32.
• [23]Beling-Nkouma D, Mveng ERP: Manuel d’histoire du Cameroun. Yaoundé: Centre d’Edition et de Production pour l’Enseignement et la Recherche; 1983.
• [24]Notaphily en.wikipedia.org/wiki/Notaphily
• [25]Clinical Laboratory Standards Institution (CLSI): Performance Standards for Antimicrobial Susceptibility Testing. Wayne PA, USA: CLSI document M100–S17; 2007. [17th Informational Supplement. Approved Standard]
• [26]Lamichhane J, Adhikary S, Gautam P, Maharjan R, Dhakal B: Risk of handling paper currency in circulation and chances of potential bacterial transmittance. J Sci Technol, Nepal 2009, 10:161-166.
• [27]Suaad SA, Laila AN: Bacterial and fungal contamination of Saudi Arabian paper currency and cell phones. Asian J Biol Sci 2011, 4:556-562.
• [28]Sabahat S, Humaira R: Evaluation of bacterial contamination of Pakistani paper currency notes (Rupee) in circulation in Karachi. Eur J Biol Sci 2011, 3:94-98.
• [29]The Study of Bacterial Contamination of Currency and Antimicrobial Capability of Metal Coins. 2012. http://www.res-medical.com/preventive-medicine webcite
• [30]Ahmed MSU, Parveen S, Nasreen T, Feroza B: Evaluation of microbial contamination of Bangladesh paper currency notes (Taka) in circulation. Adv Biol Res 2010, 4:266-271.
• [31]Nagesh B, Bhat S, Asawa K, Agarwal A: An Assessment of oral health risk associated with handling of currency notes. Int J Dent Clinics 2010, 2:14-16.
• [32]Vriesekoop F, Russell C, Alvarez-Mayorga B, Aidoo K, Yuan Q, Scannell A: Dirty money: an investigation into the hygiene status of some of the world’s currencies as obtained from food outlets. Foodborne Pathog Dis 2010, 7:1497-1502.
• [33]Al-Ghamdi AK, Abdelmalk SMA, Bamaga MS, Azhar EI, Wakid MH, Alsaied Z: Bacterial contamination of Saudi “One” Riyal paper notes. SE Asian J Trop Med 2011, 42:711-716.
• [34]Archer GL: Staphylococcus aureus, a well-armed pathogen. Clin Infect Dis 1998, 26:1179-1181.
• [35]Rowan CG, Gemmell CG, Hunter IS: Production of diarrheal enterotoxins and other potential virulence factors by veterinary isolates of Bacillus species associated with non-gastrointestinal infections. Appl Environ Microb 2003, 69:2372-2376.
• [36]Valle DD, Castilb BJM, Fernandez FMJ, Bueso SE, Casa MJM, Sanchez GJ: Endogenous Pseudomonas endophthalmitis in an immunocompetent patient. Eur J Opthalmol 2007, 17:461-463.
• [37]Sharma A, Dhanashree B: Screening of currency in circulation for bacterial contamination. Curr Sci India 2010, 100:822-825.
• [38]Ozhak-Baysan B, Alastruey-Izquierdo A, Saba R, Ogunc D, Ongut G, Timuragaoglu A, Arslan G, Cuenca-Estralla M, Rodriguez-Tudela JL: Aspergillus alliaceus and Aspergillus flavus co-infection in an acute myeloid leukemia patient. Med Mycol 2010, 48:995-999.
• [39]Ekenna O, Uba A, Chikwem JC, Mambila S, Alivu MB, Mohammed I: Relevance of moldy fungi as agents of chronic lower respiratory tract infection in patients seen in Maiduguri, Nigeria. W Afri J Med 2007, 26:117-120.
• [40]Antoniadou A: Outbreaks of zygomycosis in hospitals. Clin Microbiol Infec 2009, 5:55-59.
• [41]Gugnanai HC, Becker K, Fegeler W, Basu S, Chattopadhya D, Baveja L, Satyanarayana S, Kalghatgi T, Murlidhar A: Oropharyngeal carriage of Candida species in HIV infected patients in India. Mycoses 2003, 46:299-306.
• [42]Nkwelang G, Akoachere J-FTK, Kamga LH, Nfoncham ED, Ndip RN: Staphylococcus aureus isolates from clinical and environmental samples in a semi urban area in Cameroon: Phenotypic characterization of isolates. Afri J Microbiol Res 2009, 3:731-736.
• [43]Ndip RN, Dilonga HM, Ndip LM, Akoachere J-FTK, Nkuo-Akenji T: Pseudomonas aeruginosa recovered from clinical and environmental samples in Buea, Cameroon: current status on biotyping and antibiogram. Trop Med Int Health 2005, 10:74-81.