期刊论文详细信息
BMC Public Health
Neonatal mortality in Ethiopia: trends and determinants
Abeba Bekele3  Tedbabe Degefie2  Daniel S Telake1  Biruk Tensou3  Yared Mekonnen1 
[1] Mela Research PLC, P.O. Box 34422, Holy City Center Building, 4th Floor, Addis Ababa, Ethiopia;UNICEF Ethiopia, P.O. Box 1169, Addis Ababa, Ethiopia;Save the Children, USA, P.O. Box 387, Addis Ababa, Ethiopia
关键词: Determinants;    Trends;    Neonatal mortality;    Ethiopia;   
Others  :  1162198
DOI  :  10.1186/1471-2458-13-483
 received in 2012-08-06, accepted in 2013-05-08,  发布年份 2013
PDF
【 摘 要 】

Background

The Ethiopian neonatal mortality rate constitutes 42% of under-5 deaths. We aimed to examine the trends and determinants of Ethiopian neonatal mortality.

Methods

We analyzed the birth history information of live births from the 2000, 2005 and 2011 Ethiopia Demographic and Health Surveys (DHS). We used simple linear regression analyses to examine trends in neonatal mortality rates and a multivariate Cox proportional hazards regression model using a hierarchical approach to examine the associated factors.

Results

The neonatal mortality rate declined by 1.9% per annum from 1995 to 2010, logarithmically. The early neonatal mortality rate declined by 0.9% per annum and was where 74% of the neonatal deaths occurred. Using multivariate analyses, increased neonatal mortality risk was associated with male sex (hazard ratio (HR) = 1.38; 95% confidence interval (CI), 1.23 − 1.55); neonates born to mothers aged < 18 years (HR = 1.41; 95% CI, 1.15 − 1.72); and those born within 2 years of the preceding birth (HR = 2.19; 95% CI, 1.89 − 2.51). Winter birth increased the risk of dying compared with spring births (HR = 1.28; 95% CI, 1.08 − 1.51). Giving two Tetanus Toxoid Injections (TTI) to the mothers before childbirth decreased neonatal mortality risk (HR = 0.44; 95% CI, 0.36 − 0.54). Neonates born to women with secondary or higher schooling vs. no education had a lower risk of dying (HR = 0.68; 95% CI, 0.49 − 0.95). Compared with neonates in Addis Ababa, neonates in Amhara (HR: 1.88; 95% CI: 1.26 − 2.83), Benishangul Gumuz (HR: 1.75; 95% CI: 1.15 − 2.67) and Tigray (HR: 1.54; 95% CI: 1.01 − 2.34) regions carried a significantly higher risk of death.

Conclusions

Neonatal mortality must decline more rapidly to achieve the Millennium Development Goal (MDG) 4 target for under-5 mortality in Ethiopia. Strategies to address neonatal survival require a multifaceted approach that encompasses health-related and other measures. Addressing short birth interval and preventing early pregnancy must be considered as interventions. Programs must improve the coverage of TTI and prevention of hypothermia for winter births should be given greater emphasis. Strategies to improve neonatal survival must address inequalities in neonatal mortality by women's education and region.

【 授权许可】

   
2013 Mekonnen et al.; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150413055208776.pdf 369KB PDF download
Figure 3. 22KB Image download
Figure 2. 62KB Image download
20141202191648334.pdf 2951KB PDF download
【 图 表 】

Figure 2.

Figure 3.

【 参考文献 】
  • [1]World Health Organization: Estimates. In State of the World’s Newborns. Washington, DC: Saving Newborn Lives, Save the Children/ USA; 2001:1-49.
  • [2]Lawn JE, Cousens S, Zupan J, Lancet Neonatal Survival Steering Team: 4 million neonatal deaths: when? Where? Why? Lancet 2005, 365(9462):891-900.
  • [3]Darmstadt GL, Lawn JE, Costello A: Advancing the state of the world's newborns. Bull World Health Organ 2003, 81:224-225.
  • [4]Hyder AA, Wali SA, McGuckin J: The burden of disease from neonatal mortality: a review of South Asia and Sub-Saharan Africa. Bjog 2003, 110(10):894-901.
  • [5]Aggarwal A, Pant R, Kumar S, Sharma P, Gallagher C, Tatooles AJ, Pappas PS, Bhat G: Incidence and management of gastrointestinal bleeding with continuous flow assist devices. Ann Thorac Surg 2012, 93(5):1534-40.
  • [6]Bhutta ZA, Darmstadt GL, Hasan BS, Haws RA: Community-based interventions for improving perinatal and neonatal health outcomes in developing countries: a review of the evidence. Pediatrics 2005, 115(Suppl):519-617.
  • [7]World Data Bank: World Development Indicators. The World Bank Group; 2013. http://www.worldbank.org/en/country/ethiopia webcite
  • [8]Central Statistical Agency [Ethiopia]: Populating and housing census of Ethiopia. Ethiopia: Central Statistical Agency; 2007.
  • [9]Central Statistical Authority and ICF International: Ethiopia Demographic and Health Survey 2011. Addis Ababa, Ethiopia and Calverton, Maryland, USA: Central Statistical Agency; 2012.
  • [10]Oestergaard MZ, Inoue M, Yoshida S, Mahanani WR, Gore FM, Cousens S, Lawn JE, Mathers CD: Neonatal mortality levels for 193 countries in 2009 with trends since 1990: a systematic analysis of progress, projections, and priorities. PLoS Med 2011, 8(8):e1001080.
  • [11]Mulligan B, Degefie T, Tensou B, Matios B: Levels, Timing and Causes of Neonatal Mortality in Rural Ethiopian Communities. 13th World health congress on public health, Addis Ababa, April 23–27. Ethiopian Public Health Association; 2012.
  • [12]Rahman S, Ansari EL: Neonatal Mortality: Incidence, Correlates and Improvement Strategies. In INTECH Edited by Oliver CE, Karen OP. 2012, 37-72.
  • [13]Jahan S: Poverty and infant mortality in the Eastern Mediterranean region: a meta analysis. J Epidemiol Community Health 2008, 62:745-51.
  • [14]Rahman S, Salameh K, Bener A, Ansari EL: Socioeconomic associations of improved maternal, neonatal, and perinatal survival in Qatar. Int J Wom Health 2010, 2:311-318.
  • [15]Central Statistical Authority and ORC Macro: Ethiopia Demographic and Health Survey 2000. Ethiopia: Central Statistical Agency; 2000.
  • [16]Central Statistical Authority [Ethiopia] and ORC Macro: Ethiopia Demographic and Health Survey 2005. Addis Ababa, Ethiopia and Calverton, Maryland, USA: ; 2006.
  • [17]Mosley WH, Chen LC: An analytical framework for the study of child survival in developing countries. Popul Dev Rev 1984, 10:25-45.
  • [18]Titaley CR, Dibley MJ, Roberts CL: Type of delivery attendant, place of delivery and risk of early neonatal mortality: analyses of the 1994–2007 Indonesia Demographic and Health Surveys. Health Policy Plan 2012, 27(5):405-416.
  • [19]Titaley CR, Dibley M, Agho K, Roberts CL, Hall J: Determinants of neonatal mortality in Indonesia. BMC Public Health 2008, 8:232. BioMed Central Full Text
  • [20]Victora CG, Huttly SR, Fuchs SC, Olinto MT: The role of conceptual frameworks in epidemiological analysis: a hierarchical approach. Int J Epidemiol 1997, 26(1):224-227.
  • [21]Curtis SL: Macro International. Demographic and Health, Assessment of the quality of data used for direct estimation of infant and child mortality in DHS-II surveys. Calverton, Maryland, USA: Macro International; 1995.
  • [22]Guide to the analysis and use of household survey and census education data. UNESCO Institute for Statistics(UIS); 2004. uis/td/04-03
  • [23]Alonso V, Fuster V, Luna F: Causes of neonatal mortality in Spain (1975–98): influence of sex, rural–urban residence and age at death. J Biosoc Sci 2006, 38(4):537-51.
  • [24]D'Souza S, Chen LC: Sex differentials in mortality in rural Bangladesh. Popul Dev Rev 1980, 6(2):257-270.
  • [25]Green MS: The male predominance in the incidence of infectious diseases in children: a postulated explanation for disparities in the literature. Int J Epidemiol 1992, 21(2):381-386.
  • [26]Hobcraft JN, McDonald JW, Rutstein SO: Demographic determinants of infant and early child mortality: a comparative analysis. Population Studies 1985, 39(3):363-385.
  • [27]Shakya K, McMurray C: Neonatal mortality and maternal health care in Nepal: searching for patterns of association. J Biosoc Sci 2001, 33(1):87-105.
  • [28]Arokiasamy P, Gautam A: Neonatal mortality in the empowered action group states of India: trends and determinants. J Biosoc Sci 2008, 40(2):183-201.
  • [29]Setty-Venugopal V, Upadhyay UD: Birth spacing: three to five saves lives, P.I.P. Baltimore: Johns Hopkins University Editor; 2002:1-23.
  • [30]DaVanzo J, Hale L, Razzaque A, Rahman M: The effects of pregnancy spacing on infant and child mortality in Matlab, Bangladesh: how they vary by the type of pregnancy outcome that began the interval. Popul Stud (Camb) 2008, 62(2):131-54.
  • [31]Rutstein SO: Effects of preceding birth intervals on neonatal, infant and under-five years mortality and nutritional status in developing countries: evidence from the demographic and health surveys. Int J Gynaecol Obstet 2005, 89(Suppl 1):S7-24.
  • [32]Zenger E: Siblings' neonatal mortality risks and birth spacing in Bangladesh. Demography 1993, 30(3):477-88.
  • [33]Kamal SM: What is the association between maternal age and neonatal mortality? An analysis of the 2007 Bangladesh Demographic and Health Survey. Asia Pac J Public Health 2011. [http://lib.bioinfo.pl/pmid:22186392 webcite]
  • [34]Sharma V, Katz J, Mullany LC, Khatry SK, LeClerq SC, Shrestha SR, Darmstadt GL, Tielsch JM: Young maternal age and the risk of neonatal mortality in rural Nepal. Arch Pediatr Adolesc Med 2008, 162(9):828-35.
  • [35]Obungu W, Kizito P, Bicego GT: Macro International. Institute for Resource Development. Demographic and Health, Trends, age patterns, and determinants of early childhood mortality in Kenya. DHS Further Analysis No. 12. Macro International Inc: Calverton, Maryland; 1994.
  • [36]Dalla-Zuanna G, Rosina A: An analysis of extremely high nineteenth-century winter neonatal mortality in a local context of Northeastern Italy. Eur J Population 2011, 27(1):33-55.
  • [37]Campbell MJ, Rodrigues L, Macfarlane AJ, Murphy MF: Sudden infant deaths and cold weather: was the rise in infant mortality in 1986 in England and Wales due to the weather? Paediatr Perinat Epidemiol 1991, 5(1):93-100.
  • [38]Hare EH, Moran PA, Macfarlane A: The changing seasonality of infant deaths in England and Wales 1912–78 and its relation to seasonal temperature. J Epidemiol Community 1981, 35(2):77-82.
  • [39]Kumar R, Aggarwal AK: Body temperatures of home delivered newborns in north India. Trop Doct 1998, 28(3):134.
  • [40]Kumar V, Shearer JC, Kumar A, Darmstadt GL: Neonatal hypothermia in low resource settings: a review. J Perinatol 2009, 29(6):401-412.
  • [41]Motherhood S: Mother-Baby Package: Implementing safe motherhood in countries. Geneva, Switzerland: WHO/FHE/MSM/94.11; 1994.
  • [42]World Health Organization, Thermal Protection of the Newborn: A Practical Guide. Report No.: WHO/RHT/MSM/97.2. Geneva: World Health Organization; 1997.
  • [43]Rahman M, Chen LC, Chakraborty J, Yunus M, Chowdhury AI, Sarder AM, Bhatia S, Curlin GT: Use of tetanus toxoid for the prevention of neonatal tetanus. 1. Reduction of neonatal mortality by immunization of non-pregnant and pregnant women in rural Bangladesh. Bull World Health Organ 1982, 60(2):261.
  • [44]Titaley CR, Dibley MJ, Roberts CL, Hall J, Agho K: Iron and folic acid supplements and reduced early neonatal deaths in Indonesia. Bull World Health Organ 2010, 88(7):500-508.
  • [45]Lawn JE, Kerber K: Opportunities for Africa's Newborns: Practical data, policy and programmatic support for newborn care in Africa. In The Partnership for Maternal, Newborn and Child Health. Mills Litho, Cape Town, South Africa: ; 2006.
  • [46]Hatt L, Stanton C, Ronsmans C, Makowiecka K, Adisasmita A: Did professional attendance at home births improve early neonatal survival in Indonesia? Health Policy Plan 2009, 24(4):270-278.
  • [47]Basu AM, Stephenson R: Low levels of maternal education and the proximate determinants of childhood mortality: a little learning is not a dangerous thing. Soc Sci Med 2005, 60(9):2011-2023.
  • [48]Caldwell JC: Education as a factor in mortality decline an examination of Nigerian data. Popul Stud 1979, 33(3):395-413.
  • [49]Fort AL, Kothari MT, Abderrahim N: Association Between Maternal, Birth, and Newborn Characteristics and Neonatal Mortality in Five Asian Countries. DHS working paper. Calverton, Maryland, USA: Macro International; 2008.
  • [50]Ware H: Effects of maternal education, women's roles, and child care on child mortality. Popul Dev Rev 1984, 10:191-214.
  • [51]Macassa G, Hallqvist J, Lynch JW: Inequalities in child mortality in sub-Saharan Africa: A social epidemiologic framework. Afr J Health Sci 2011, 18(1–2):14-26.
  • [52]Hill K: Approaches to the measurement of childhood mortality: a comparative review. Popul Index 1991, 57(3):368-82.
  • [53]Hall S: Neonatal Mortality in Developing Countries: What can we learn from DHS data?. University of Southampton, UK: Southampton Statistical Sciences Research Institute; 2005.
  • [54]Mahy M: Childhood mortality in the developing world: a review of evidence from the Demographic and Health Surveys. Calverton, Maryland, USA: MEASURE DHS+, Macro International; 2003.
  文献评价指标  
  下载次数:11次 浏览次数:5次