Impact of psychosocial factors on cardiovascular morbimortality: a prospective cohort study

BMC Cardiovascular Disorders

Miguel-Ángel Muñoz⁹  Valentina Ruiz-Gutiérrez⁶  Rosa-Maria Lamuela-Raventos⁶  José-V Sorlí¹  Josep Basora⁶  Javier Díez-Espino²  Emilio Ros^1,10  Xavier Pintó⁶  Lluís Serra-Majem⁶  José Lapetra^1,10  Miquel Fiol^1,10  Enrique Gómez-Gracia⁶  Fernando Arós⁷  Dolores Corella¹  Olga Castañer⁴  Jordi Salas-Salvadó⁵  Miguel-Angel Martínez-González⁸  Ramón Estruch³  Cília Mejía-Lancheros^1,11 

[1]Department of Preventive Medicine, University of Valencia, Valencia, Spain

[2]Centro de Salud de Tafalla, Servicio Navarro de Salud, University of Navarra, Pamplona, Spain

[3]Department of Internal Medicine of Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain

[4]Cardiovascular Risk and Nutrition Research Group of Institute Hospital del Mar (IMIM), Barcelona, Spain

[5]Human Nutrition Department, Hospital Universitari Sant Joan, Institut d’Investigació Sanitaria Pere Virgili, Universitat Rovira i Virgili, Reus, Spain

[6]PREDIMED (Prevención con Dieta Mediterránea) Network (RD 06/0045), Instituto de Salud Carlos III, Madrid, Spain

[7]Department of Cardiology, University Hospital of Alava, Vitoria, Spain

[8]Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain

[9]Institut d’Investigació en Atenció Primària IDIAP-Jordi Gol, Barcelona, Spain

[10]CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain

[11]Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain

关键词: Health inequalities;    Social support;    Depression;    Socioeconomic position;    Educational level;    Cardiovascular death;    Acute myocardial infarction;    Stroke;   

Others  :  1088437
DOI  :  10.1186/1471-2261-14-135

 received in 2014-06-27, accepted in 2014-09-22,  发布年份 2014

【 摘 要 】

Background

Whilst it is well known that psychosocial determinants may contribute to cardiovascular diseases (CVD), data from specific groups are scarce. The present study aims to determine the contribution of psychosocial determinants in increasing the risk of cardiovascular events (myocardial infarction and stroke), and death from CVD, in a high risk adult population.

Methods

Longitudinal prospective study of 7263 patients (57.5% women), mean age 67.0 (SD 6.2) free from CVD but at high risk, with a median follow-up of 4.8 years (from October 2003 to December 2010). The Hazard Ratios (HRs) of cardiovascular events (myocardial infarction, stroke, and death from cardiovascular causes) related to educational attainment, diagnosed depression (based on medical records), and low social support (number of people living in the household) were estimated by multivariate Cox regression models.

Results

Stroke incidence was associated with low educational level in the whole population (HR: 1.83, 95% CI: 1.09–3.09), and especially in men (HR: 2.11, 95% CI 1.09–4.06). Myocardial infarction and CVD mortality were not associated with any of the psychosocial factors considered.

Conclusion

Adults with low educational level had a higher risk of stroke. Depression and low social support were not associated with CVD incidence.

Trial registration

Clinical trial registration information unique identifier: ISRCTN35739639.

【 授权许可】

   
2014 Mejía-Lancheros et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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