BMC Research Notes | |
Iodine deficiency among goiter patients in rural South Sudan | |
Jane Odubu Fualal2  Nicholas Kisa2  Charles Ibingira1  Moses Galukande2  Chep C Chuot2  | |
[1] Anatomy Department, College of Health Sciences, Makerere University, Kampala, Uganda;Surgery Department, College of Health Sciences, Makerere University, Kampala, Uganda | |
关键词: Rural south Sudan; Deficiency; Iodine; Goiter; | |
Others : 1127150 DOI : 10.1186/1756-0500-7-751 |
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received in 2013-11-08, accepted in 2014-10-14, 发布年份 2014 | |
【 摘 要 】
Background
It is estimated that 2.2 billion or approximately 30% of the world’s population live in iodine-deficient areas. In a 2005 study households consuming iodized salt in South Sudan increased from 40% to 73%. Despite this achievement, there are still many goiter cases in rural South Sudan and iodine deficiency remains as a major public health problem in this part of sub Saharan Africa.
The purpose of this study therefore was to determine the prevalence of iodine deficiency among rural Southern Sudan goiter patients.
Methods
A cross-sectional study was carried out in three South Sudan counties, adults with goiter were from three centers following a mobilization campaign that lasted 4 weeks for free medical care. They were clinically evaluated and completed interviewer administered questionnaires to determine their age, gender, diet, family history, drug history, and medical history. Urine samples were then taken for urinary iodine levels. The outcome was iodine deficiency measured as urinary iodine less than 100 μg per/ L. Multiple logistic regression was used to establish the factors associated with iodine deficiency in South Sudan. Ethical approval was obtained.
Results
A total of 286 goitre patients were recruited. The mean age was 38 years (SD 9), 262(92%) were females (F: M ratio 11:1), and 257(90%) were rural- peasants, 25% (20/286) had moderate to severe iodine deficiency. 174(62%) consumed non-iodized salts.
Conclusion
Iodine deficiency is highly prevalent among rural South Sudan communities and a likely cause for goiters. Rural poor women are highly vulnerable.
【 授权许可】
2014 Chuot et al.; licensee BioMed Central Ltd.
【 预 览 】
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【 图 表 】
Figure 1.
【 参考文献 】
- [1]Anderson M, de Benoist B, Darnton-Hill I, Delange F: Iodine Deficiency in Europe: A Continuing Public Health Problem. WHO/UNICEF; 2007. ISBN 978241593960 http://www.who.int/nutrition/publications/VMNIS_Iodine_deficiency_in_Europe.pdf webcite
- [2]De Benoist , Mclean E, Anderson M, Rogers L: Iodine deficiency in 2007: global progress since 2003. Food Nutr Bull 2008, 29(3):195-202.
- [3]Health Information 2014. http://www.who.int/healthinfo/global-burden-disease/GlobalHealthrisks-report-part2.pdf webcite
- [4]Gaffar AM, Mahfouz MS: Peace impact on health: population access to iodized salt in south Sudan in post-conflict period. Croat Med J 2005, 52(2):178-182.
- [5]Hill AG, Mwangi I, Wagana L: Thyroid disease in a rural Kenyan hospital: a case control study. East Afr Med J 2004, 81(12):631-633.
- [6]Watayachanga Chirwa P: Urinary iodine excretion in goiter patients and controls at Mulago Hospital. Thesis Report 1999.
- [7]Bimenya GS, Olico O, Dentos K, Mbona N, Byarugaba W: Monitoring the severity of iodine deficiency disorders in Uganda. Afr Health Sci 2002, 2:63-68.
- [8]Zimmerman MB, Jooste PL, Pandar CS: Iodine deficiency disorders. Lancet 2008, 372(9645):1251-1262.
- [9]Downie R: The state of public health in South Sudan: critical condition. 2014. http://www.csis.org/files/publication/121114-downie_Healthsudan-web.pdf webcite
- [10]South Sudan: Fifth Population and Housing Census. 2009. http://www.ssnbs.org webcite
- [11]Indicators for Assessing Iodine Deficiency Disorders and the Control through Salt Iodization In WHO, UNICEF & ICCIDD. Geneva: WHO/NUT/94.6, WHO; 1994:1-55.
- [12]Orlo HC, Quan-Yang D, Electron K: Textbook of Endocrine Surgery. 2nd edition. Philadelphis: Elsevier Saunders; 2005. [Chapters 4–6]
- [13]Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers 3rd edition. Geneva: WHO Press; 2007. ISBN 978 92 4159582 7
- [14]Ogbera AO, Kuku SF: Epidemiology of thyroid diseases in Africa. Indian J Endocrinol Metab 2011, 15(Suppl 2):S82-S88.
- [15]Delenge F: Thyroid volume and Urinary iodine in European School Children: standardization of values for assessment of iodine Deficiency. Eur J Endocrinol 1997, 136(2):180-187,19.
- [16]Dunn JT, Crutchfield HE, Gutekunst R, Dunn AD: Methods for Measuring Iodine in Urine. The Netherlands: International Council for Control of Iodine Deficiency Disorders; 1993.
- [17]Osman Sandell EB, Kolthoff IM: Micro determination of iodine by a catalytic method. Mikrochemica Acta 1937, 1:9-25.
- [18]Eltom M, Elmahdi EM, Salih MA, Mukhtar E, Omer MI: Anew focus of endemic goiter in the Sudan. Trop Geogr Med 1985, 37(1):15-21.
- [19]Eltom M, Salih MA, Boström H, Dahlberg PA: Differences in aetiology and thyroid function in endemic goiter between rural and urban areas of the Darfur region of the Sudan. Acta Endocrinol (Copenh) 1985, 108(3):356-360.
- [20]Eltom M, Hofvander Y, Torelm I, Fellström B: Endemic goiter in the Darfur region (Sudan). Epidemiology and aetiology. Acta Med Scand 1984, 215(5):467-475.
- [21]Black MM: Micronutrient deficiencies and cognitive functioning. J Nutr 2003, 133(11Suppl 2):3927S-3931S.
- [22]Abuye CY, Berhane Y, Akalu G, Getahun Z, Ersumoo T: Prevalence of goiter in children 6 to 12 years of age in Ethiopia. Food Nutr Bull 2007, 28(4):391-398.
- [23]Cherinet A, Kelbessa U: Determinants of iodine deficiency in school children in different regions of Ethiopia. East Afr Med J 2000, 77(3):133-137.
- [24]Vanderpump MPJ: The epidemiology of thyroid diseases. In The thyroid: A Fundamental and Clinical Text. 9th edition. Edited by Werner and Ingbor’s, Braverman LE, Utiger RD. Philidelphia: JB Lippincott – Raven; 2005:398-496.