BMC Musculoskeletal Disorders | |
Consecutive assessment of FA and ADC values of normal lumbar nerve roots from the junction of the dura mater | |
Hiroshi Yoshioka1  Eiko Yamabe1  Toshinori Sakai2  Ryo Miyagi1  | |
[1] Department of the Radiological Sciences, University of California, Irvine, School of Medicine, Irvine 92868, CA, USA;Department of Orthopedics, The University of Tokushima Graduate School, Tokushima, Japan | |
关键词: Apparent diffusion coefficient (ADC); Fractional anisotropy (FA); Diffusion tensor imaging (DTI); Diffusion weighted imaging (DWI); | |
Others : 1227739 DOI : 10.1186/s12891-015-0576-4 |
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received in 2015-02-02, accepted in 2015-05-08, 发布年份 2015 | |
【 摘 要 】
Background
Diffusion weighted imaging (DWI) and diffusion tensor imaging (DTI) are widely used in the evaluation of the central nervous system and recently have been reported as a potential tool for diagnosis of the peripheral nerve or the lumbar nerve entrapment. The purpose of this study was to evaluate consecutive changes in apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values of normal lumbar nerve roots from the junction of the dura mater.
Methods
The lumbar spinal nerves were examined in 6 male healthy volunteers (mean age, 35 years) with no experiences of sciatica, with a 3.0-T MR unit using a five-element phased-array surface coil. DTI was performed with the following imaging parameters: 11084.6/73.7 ms for TR/TE; b-value, 800 s/mm2; MPG, 33 directions; slice thickness, 1.5 mm; and total scan time, 7 min 35 s. ADC and FA values at all consecutive points along the L4, L5 and S1 nerves were quantified on every 1.5 mm slice from the junction of the dura mater using short fiber tracking.
Results
ADC values of all L4, 5, and S1 nerve roots decreased linearly up to 15 mm from the dura junction and was constant distally afterward. ADC values in the proximal portion demonstrated S1 > L5 > L4 (p < 0.05). On the other hand, FA values increased linearly up to 15 mm from the dura junction, and was constant distally afterward. FA values in the proximal portion showed L4 > L5 > S1 (p < 0.05).
Conclusion
Our study demonstrated that ADC and FA values of each L4, 5, and S1 at the proximal portion from the junction of the dura matter changed linearly. It would be useful to know the normal profile of DTI values by location of each nerve root so that we can detect subtle abnormalities in each nerve root.
【 授权许可】
2015 Miyagi et al.
【 预 览 】
Files | Size | Format | View |
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20150929033804584.pdf | 800KB | download | |
Fig. 4. | 25KB | Image | download |
Fig. 3. | 30KB | Image | download |
Figure 6. | 35KB | Image | download |
Fig. 1. | 24KB | Image | download |
【 图 表 】
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