期刊论文详细信息
BMC Research Notes
Upper limb musculoskeletal abnormalities in type 2 diabetic patients in low socioeconomic strata in Pakistan
Ishaque Sheikh2  Ishaq Ghauri2  Rashid M khan1  Shaista A Siddiqi2  Lubna Wahid2  Saera Suhail Kidwai2 
[1] MS (neuropharmacology), Karachi, Pakistan;Jinnah Medical College Hospital, SR-6, Sector 7-A, Korangi Industrial Area, Karachi, 75440, Pakistan
关键词: Pakistan;    Trigger finger;    Dupuytren’s contracture;    Carpal tunnel syndrome;    Adhesive capsulitis;    Type 2 Diabètes mellitus;   
Others  :  1144999
DOI  :  10.1186/1756-0500-6-16
 received in 2012-08-10, accepted in 2013-01-11,  发布年份 2013
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【 摘 要 】

Background

Musculoskeletal manifestations of diabetes in the upper limb are well recognized. No data has been available in this regard from Pakistan. Our aim was to find out the frequency of upper limb musculoskeletal abnormalities in diabetic patients.

Methods

This was an observational study in which type 2 diabetes patients attending our diabetic clinic were enrolled along with age and gender matched controls. Data was analyzed on SPSS 16.

Results

In total, 210 Type 2 diabetics (male 34.3%, female 65.7%) and 203 controls (male 35%, female 65%) were recruited. The mean age was 50.7± 10.2 years in diabetic group as compared to 49.5±10.6 years in the control group. The frequencies of hand region abnormalities were significantly higher in the diabetic subjects as compared to the controls (20.4%, p-value <0.001). Limited joint mobility (9.5% vs 2.5%), carpal tunnel syndrome (9% vs 2%), trigger finger (3.8% vs 0.5%), and dupuytren’s contracture (1% vs 0%) were found more frequent as compared to controls (all p-values <0.05). In the shoulder region of diabetic subjects, adhesive capsulitis and tendonitis was found in 10.9% and 9.5% respectively as compared to 2.5% and 2% in control group [p- value <0.001]. A weak but positive relationship was observed between age and duration of diabetes with these upper limb abnormalities. However, no correlation was found between the frequencies of these abnormalities with control of diabetes.

Conclusion

A higher frequency of upper limb musculoskeletal abnormalities was observed in Type 2 diabetic patients as compared to control group.

【 授权许可】

   
2013 Kidwai et al.; licensee BioMed Central Ltd.

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【 参考文献 】
  • [1]Qidwai W, Ashfaq T: Imminent Epidemic of Diabetes Mellitus in Pakistan: Issues and challenges for Health Care Providers. JLUMHS 2010, 09:112.
  • [2]Schiavon F, Circhetta C, Dani L: The diabetic hand. Reumatismo 2004, 56:139-142.
  • [3]Crispin JC, Alcocer VJ: Rheumatic manifestations of diabetes mellitus. Am J Med 2003, 14:753-757.
  • [4]Starkman HS, Gleason RE, Rand LI, Miller DE, Soeldner JS: Limited joint mobility (LJM) of the hand in patients with diabetes mellitus: relation to chronic complications. Ann Rheum Dis 1986, 45:130-135.
  • [5]Jennings AM, Milner PC, Ward JD: Hand abnormalities are associated with the complications of diabetes in type 2 diabetes. Diabet Med 1989, 6:43-47.
  • [6]International Diabetes Federation: Diabetes Atlas. 3rd edition. Brussels, Belgium: International Diabetes Federation; 2006.
  • [7]The Nation: WHO ranks Pakistan 7th on diabetes prevalence list [online] 2008 [cited 2010 July 18]. Available from: http://www.nation.com.pk/pakistan-news-newspaper-daily-english-online/Regional/Karachi/15-Nov-2008/WHO-ranks-Pakistan-7th-on-diabetes-prevalence-list webcite.
  • [8]International Diabetic Federation Diabetes [online] 2006 [cited 2010 July 18]. Available from: http://www.idf.org/webdata/docs/background_dis_final.pdf webcite.
  • [9]Khuwaja AK, Fatmi Z, Soomro WB, Khuwaja NK: Risk factors for cardiovascular disease in school Children: a pilot study. J Pak Med Assoc 2003, 53:396-400.
  • [10]Roquelaure Y, Ha C, Rouillon C, Fouquet N, Leclerc A, Descatha A, et al.: Risk factors for upper-extremity musculoskeletal disorders in the working population. Arthritis Rheum 2009, 61:1425-1434.
  • [11]Arkkila PE, Gautier JF: Musculoskeletal disorders in diabetes mellitus: an update. Best Pract Res Clin Rheumatol 2003, 17:945-970.
  • [12]Del Rosso A, Cerinic MM, De Giorgio F, Minari C, Rotella CM, Seghier G: Rheumatological manifestations in diabetes mellitus. Curr Diabetes Rev 2006, 4:455-466.
  • [13]Dyck PJ, Kratz KM, Karnes JL, Litchy WJ, Klein R, Pach JM, et al.: The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: the Rochester Diabetic Neuropathy Study. Neurology 1993, 43:817-824.
  • [14]Makepeace A, Davis AW, Bruce GD, Davis T: Incidence and determinants of carpal tunnel decompression surgery in type 2 diabetes. The Fremantle diabetes study diabetes care 2008, 31:498-500.
  • [15]Ardic F, Soyupek F, Kahraman Y, Yorgancıoglu R: The musculoskeletal complications seen in type II diabetics: predominance of hand involvement. Clin Rheumatol 2003, 22:229-233.
  • [16]Cagliero E, Apruzzese W, Perlmutter GS, Nathan DM: Musculoskeletal disorders of the hand and shoulder in patients with Diabetes Mellitus. Am J Med 2002, 112:487-490.
  • [17]Ramchurn N, Mashamba C, Leitch E, Arutchelvam V, Narayanan K, Weaver J, et al.: Upper limb musculoskeletal abnormalities and poor metabolic control in diabetes. Eur J Intern Med 2009, 20:718-721.
  • [18]Parada-Turska J, Majdan M: The musculoskeletal system in diabetic patients. Postepy Hig Med Dosw 2005, 59:236-244.
  • [19]Douloumpakas I, Pyrpasopoulou A, Triantafyllou A, Sampanis C, Aslanidis S: Prevalence of musculoskeletal disorders in patients with type 2 diabetes mellitus: a pilot study. Hippokratia 2007, 11:216-218.
  • [20]Smith LL, Burnet SP, McNeil JD: Musculoskeletal manifestations of Diabetes mellitus. Br J Sports Med 2003, 37:30-35.
  • [21]Sarkar P, Pain S, Sarkar RN, Ghosal R, Mandal SK, Banerjee R: Rheumatological manifestations in Diabetes mellitus. J Indian Med Assoc 2008, 106:593-594.
  • [22]National Institute of Health and Clinical Excellence: NICE Clinical Guideline 66-Type 2 Diabetes. London: NICE; 2008. http://www.nice.org.uk/CG066 webcite.
  • [23]Cornblath DR: Diabetic neuropathy: diagnostic methods. Adv stud Med 2004, 4:650-661.
  • [24]Harrington JM, Carter JT, Birrell L, Gompertz D: Surveillance case definitions for work related upper limb pain syndromes. Occup Environ Med 1998, 55:264-271.
  • [25]Gamstedt A, Holm-Glad J, Ohlson CG, Sundstrom M: Hand abnormalities are strongly associated with the duration of diabetes mellitus. J Intern Med 1993, 234:189-193.
  • [26]Bayat A, McGrouther DA: Management of Dupuytren’s disease-clear advice for an elusive condition. Ann R Coll Surg Engl 2006, 88:3-8.
  • [27]Stadner F, Ulreich A, Pfeiffer KP: Dupuytren’s contracture as a concomitant disease in diabetes mellitus. Wien Med Wochenschr 1987, 137:89-92.
  • [28]Mikkelsen OA: The prevalence of Dupuytren’s disease in Norway: a study in a representative population sample of the municipality of Haugesund. Acta Chir Scand 1972, 138:695-700.
  • [29]Attali P, Ink O, Pelletier I, Vernier C, Jean F, Moulton L, et al.: Dupuytren’s contracture, alcohol consumption, and chronic liver disease. Arch Intern Med 1987, 147:1065-1067.
  • [30]Tighe CB, Oakley WS: The prevalence of a diabetic condition and adhesive capsulitis of the shoulder. South Med J 2008, 101:591-595.
  • [31]Lawson PM, Maneschi F, Kohner EM: The relationship of hand abnormalities to diabetes and diabetic retinopathy. Diabetes Care 1983, 6:140-143.
  • [32]Renard E, Jacques D, Chammas M, Poirier JL, Bonifacj C, Jaffiol C, et al.: Increased prevalence of soft tissue hand lesions in type 1 and type 2 diabetes mellitus: various entities and associated significance. Diabetes Metab 1994, 20:513-521.
  • [33]Chammas M, Bousquet P, Renard E, Poirier JL, Jaffiol C, Allieu Y: Dupuytren’s disease, carpal tunnel syndrome, trigger finger, and diabetes mellitus. J Hand Surg 1995, 20:109-114.
  • [34]Comi G, Lozza L, Galardi G, Ghilardi MF, Medaglini S, Canal N: Presence of carpal tunnel syndrome in diabetics: effect of age, sex, diabetes duration and polyneuropathy. Acta Diabetol Lat 1985, 22:259-262.
  • [35]Singh R, Gamble G, Cundy T: Lifetime risk of symptomatic carpal tunnel syndrome in type 1 diabetes. Diabet Med 2005, 22:625-630.
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