Ectopic pregnancy rates with day 3 versus day 5 embryo transfer: a retrospective analysis

BMC Pregnancy and Childbirth

Sunny H Jun¹  Amin A Milki¹ 

[1] Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, U.S.A

关键词: IVF;    Embryo transfer;    Ectopic pregnancy;    Blastocyst;   

Others  :  1165817
DOI  :  10.1186/1471-2393-3-7

 received in 2003-09-24, accepted in 2003-11-07,  发布年份 2003

【 摘 要 】

Background

Blastocyst transfer may theoretically decrease the incidence of ectopic pregnancy following IVF-ET in view of the decreased uterine contractility reported on day 5. The purpose of our study is to specifically compare the tubal pregnancy rates between day 3 and day 5 transfers.

Methods

A retrospective analysis of all clinical pregnancies conceived in our IVF program since 1998 was performed. The ectopic pregnancy rates were compared for day 3 and day 5 transfers.

Results

There were 623 clinical pregnancies resulting from day 3 transfers of which 22 were ectopic (3.5%). In day 5 transfers, there were 13 ectopic pregnancies out of 333 clinical pregnancies (3.9%). The difference between these rates is not statistically significant (P = 0.8).

Conclusions

Our data suggests that the ectopic pregnancy rate is not reduced following blastocyst transfer compared to day 3 transfer. While there may be several benefits to extended culture in IVF, the decision to offer blastocyst transfer should be made independently from the issue of ectopic pregnancy risk.

【 授权许可】

   
2003 Milki and Jun; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

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