期刊论文详细信息
BMC Musculoskeletal Disorders
Two-stage hip revision arthroplasty with a hexagonal modular cementless stem in cases of periprosthetic infection
Steffen Hoell3  Jendrik Hardes3  Arne Streitbürger3  Kiriakos Daniilidis1  Karsten Becker2  Georg Gosheger3  Dino Schulz3  Ralf Dieckmann3 
[1] Department of Orthopedics, Hannover University Hospital, Anna-von-Borries-Strasse 1-7, 30625 Hannover, Germany;Institute of Medical Microbiology, Münster University Hospital, Albert-Schweitzer-Campus 1, A1, 48149 Münster, Germany;Department of Orthopedics and Tumor Orthopedics, Münster University Hospital, Albert-Schweitzer-Campus 1, A1, 48149 Münster, Germany
关键词: Hexagonal;    Modular;    Cementless;    Hip arthroplasty;    Periprosthetic infection;    Two-stage revision;   
Others  :  1091467
DOI  :  10.1186/1471-2474-15-398
 received in 2014-07-08, accepted in 2014-11-18,  发布年份 2014
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【 摘 要 】

Background

Two-stage revision arthroplasty is today regarded as the gold standard treatment method for deep prosthetic joint infection. The aim of the present study was to evaluate clinical and functional outcomes with the Modular Universal Tumor And Revision System (MUTARS) RS stem in patients undergoing two-stage revisions.

Methods

The functional and clinical outcomes for 43 patients who had undergone two-stage revision procedures for PJI were analyzed in a retrospective study. The minimum follow-up period was 24 months. Shorter follow-up periods were only observed when there were complications such as loosening or recurrent infection. The mean follow-up period was 3.86 years (range 7 months to 11.6 years).

Results

The success rate with infection control for PJI was 93%. Reinfection occurred in four cases (7%). The risk of reinfection after MRSA infection was 20.5 times greater (P >0.01) than with sensitive or unknown bacteria. Two aseptic loosening occurred after 7 and 20 months. The average Harris Hip Score was 80 (range 62–93).

Conclusion

This retrospective study showed a 93% rate of eradication using specific antibiotic therapy. With the modular MUTARS RS stem, there was a low rate of aseptic loosening of 4.6%. MRSA infection was identified as a risk factor for reinfection. The two-stage procedure with modular cementless implants used is therefore appropriate for treating periprosthetic infections associated with hip endoprostheses.

【 授权许可】

   
2014 Dieckmann et al.; licensee BioMed Central Ltd.

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【 参考文献 】
  • [1]Gemeinsamer Bundesausschuss: Hüftendoprothesenversorgung Abschlussbericht 2010. Aqua - Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen; 2012.
  • [2]Jamsen E, Furnes O, Engesaeter LB, Konttinen YT, Odgaard A, Stefansdottir A, Lidgren L: Prevention of deep infection in joint replacement surgery. Acta Orthop 2010, 81:660-666.
  • [3]Wilson J, Charlett A, Leong G, McDougall C, Duckworth G: Rates of surgical site infection after hip replacement as a hospital performance indicator: analysis of data from the English mandatory surveillance system. Infect Control Hosp Epidemiol 2008, 29:219-226.
  • [4]Zimmerli W, Trampuz A, Ochsner PE: Prosthetic-joint infections. N Engl J Med 2004, 351:1645-1654.
  • [5]Fink B, Grossmann A, Fuerst M, Schafer P, Frommelt L: Two-stage cementless revision of infected hip endoprostheses. Clin Orthop Relat Res 2009, 467:1848-1858.
  • [6]Haddad FS, Muirhead-Allwood SK, Manktelow AR, Bacarese-Hamilton I: Two-stage uncemented revision hip arthroplasty for infection. J Bone Joint Surg 2000, British volume 82:689-694.
  • [7]Duncan CP, Masri BA: The role of antibiotic-loaded cement in the treatment of an infection after a hip replacement. Instr Course Lect 1995, 44:305-313.
  • [8]Estok DM 2nd, Harris WH: Long-term results of cemented femoral revision surgery using second-generation techniques. An average 11.7-year follow-up evaluation. Clin Orthop Relat Res 1994, 299:190-202.
  • [9]Kim YH, Kim JS, Park JW, Joo JH: Cementless revision for infected total hip replacements. J Bone Joint Surg 2011, British volume 93:19-26.
  • [10]Della Valle CJ, Shuaipaj T, Berger RA, Rosenberg AG, Shott S, Jacobs JJ, Galante JO: Revision of the acetabular component without cement after total hip arthroplasty. A concise follow-up, at fifteen to nineteen years, of a previous report. J Bone Joint Surg 2005, American Volume 87:1795-1800.
  • [11]Weeden SH, Paprosky WG: Minimal 11-year follow-up of extensively porous-coated stems in femoral revision total hip arthroplasty. J Arthroplasty 2002, 17:134-137.
  • [12]Fehring TK, Calton TF, Griffin WL: Cementless fixation in 2-stage reimplantation for periprosthetic sepsis. J Arthroplasty 1999, 14:175-181.
  • [13]Hofmann AA, Goldberg TD, Tanner AM, Cook TM: Ten-year experience using an articulating antibiotic cement hip spacer for the treatment of chronically infected total hip. J Arthroplasty 2005, 20:874-879.
  • [14]Koo KH, Yang JW, Cho SH, Song HR, Park HB, Ha YC, Chang JD, Kim SY, Kim YH: Impregnation of vancomycin, gentamicin, and cefotaxime in a cement spacer for two-stage cementless reconstruction in infected total hip arthroplasty. J Arthroplasty 2001, 16:882-892.
  • [15]Kraay MJ, Goldberg VM, Fitzgerald SJ, Salata MJ: Cementless two-staged total hip arthroplasty for deep periprosthetic infection. Clin Orthop Relat Res 2005, 441:243-249.
  • [16]Macheras GA, Koutsostathis SD, Kateros K, Papadakis S, Anastasopoulos P: A two stage re-implantation protocol for the treatment of deep periprosthetic hip infection. Mid to long-term results. Hip Int 2012, 22(Suppl 8):S54-S61.
  • [17]Neumann DR, Hofstaedter T, List C, Dorn U: Two-stage cementless revision of late total hip arthroplasty infection using a premanufactured spacer. J Arthroplasty 2012, 27:1397-1401.
  • [18]Valle CJ, Paprosky WG: Classification and an algorithmic approach to the reconstruction of femoral deficiency in revision total hip arthroplasty. J Bone Joint Surg 2003, American volume 85-A(Suppl 4):1-6.
  • [19]Harris WH: Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. J Bone Joint Surg 1969, American volume 51:737-755.
  • [20]Horan TC, Andrus M, Dudeck MA: CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008, 36:309-332.
  • [21]Gebert C, Wessling M, Gotze C, Gosheger G, Hardes J: The Modular Universal Tumour and Revision System (MUTARS(R)) in endoprosthetic revision surgery. Int Orthop 2010, 34:1261-1265.
  • [22]Anagnostakos K, Furst O, Kelm J: Antibiotic-impregnated PMMA hip spacers: current status. Acta Orthop 2006, 77:628-637.
  • [23]Cooper HJ, Della Valle CJ: The two-stage standard in revision total hip replacement. Bone Joint J 2013, 95-B:84-87.
  • [24]Masri BA, Panagiotopoulos KP, Greidanus NV, Garbuz DS, Duncan CP: Cementless two-stage exchange arthroplasty for infection after total hip arthroplasty. J Arthroplasty 2007, 22:72-78.
  • [25]Nestor BJ, Hanssen AD, Ferrer-Gonzalez R, Fitzgerald RH Jr: The use of porous prostheses in delayed reconstruction of total hip replacements that have failed because of infection. J Bone Joint Surg 1994, American volume 76:349-359.
  • [26]Wilson MG, Dorr LD: Reimplantation of infected total hip arthroplasties in the absence of antibiotic cement. J Arthroplasty 1989, 4:263-269.
  • [27]Bohm P, Bischel O: Femoral revision with the Wagner SL revision stem: evaluation of one hundred and twenty-nine revisions followed for a mean of 4.8 years. J Bone Joint Surg 2001, American volume 83-A:1023-1031.
  • [28]Hedley AK, Gruen TA, Ruoff DP: Revision of failed total hip arthroplasties with uncemented porous-coated anatomic components. Clin Orthop Relat Res 1988, 235:75-90.
  • [29]Mcinnis DP, Horne G, Devane PA: Femoral revision with a fluted, tapered, modular stem seventy patients followed for a mean of 3.9 years. J Arthroplasty 2006, 21:372-380.
  • [30]Paprosky WG, Greidanus NV, Antoniou J: Minimum 10-year-results of extensively porous-coated stems in revision hip arthroplasty. Clin Orthop Relat Res 1999, 369:230-242.
  • [31]Colyer RA, Capello WN: Surgical treatment of the infected hip implant. Two-stage reimplantation with a one-month interval. Clin Orthop Relat Res 1994, 298:75-79.
  • [32]Fink B: Revision of late periprosthetic infections of total hip endoprostheses: pros and cons of different concepts. Int J Med Sci 2009, 6:287-295.
  • [33]Garvin KL, Evans BG, Salvati EA, Brause BD: Palacos gentamicin for the treatment of deep periprosthetic hip infections. Clin Orthop Relat Res 1994, 298:97-105.
  • [34]Leunig M, Chosa E, Speck M, Ganz R: A cement spacer for two-stage revision of infected implants of the hip joint. Int Orthop 1998, 22:209-214.
  • [35]Mcdonald DJ, Fitzgerald RH Jr, Ilstrup DM: Two-stage reconstruction of a total hip arthroplasty because of infection. J Bone Joint Surg 1989, American volume 71:828-834.
  • [36]Kuzyk PR, Dhotar HS, Sternheim A, Gross AE, Safir O, Backstein D: Two-stage revision arthroplasty for management of chronic periprosthetic hip and knee infection: techniques, controversies, and outcomes. J Am Acad Orthop Surg 2014, 22:153-164.
  • [37]Zimmerli W: Infection and musculoskeletal conditions: prosthetic-joint-associated infections. Best practice & research. Clin Rheumatol 2006, 20:1045-1063.
  • [38]Bjerke-Kroll BT, Christ AB, Mclawhorn AS, Sculco PK, Jules-Elysee KM, Sculco TP: Periprosthetic joint infections treated with two-stage revision over 14 years: an evolving microbiology profile. J Arthroplasty 2014, 29:877-882.
  • [39]Jackson WO, Schmalzried TP: Limited role of direct exchange arthroplasty in the treatment of infected total hip replacements. Clin Orthop Relat Res 2000, 381:101-105.
  • [40]Kilgus DJ, Howe DJ, Strang A: Results of periprosthetic hip and knee infections caused by resistant bacteria. Clin Orthop Relat Res 2002, 404:116-124.
  • [41]Lim SJ, Park JC, Moon YW, Park YS: Treatment of periprosthetic hip infection caused by resistant microorganisms using 2-stage reimplantation protocol. J Arthroplasty 2009, 24:1264-1269.
  • [42]Wirtz DC, Niethard FU: Etiology, diagnosis and therapy of aseptic hip prosthesis loosening–a status assessment. Zeitschrift fur Orthopadie und ihre Grenzgebiete 1997, 135:270-280.
  • [43]Dohmae Y, Bechtold JE, Sherman RE, Puno RM, Gustilo RB: Reduction in cement-bone interface shear strength between primary and revision arthroplasty. Clin Orthop Relat Res 1988, 236:214-220.
  • [44]Cordero-Ampuero J, De Dios M: What are the risk factors for infection in hemiarthroplasties and total hip arthroplasties? Clin Orthop Relat Res 2010, 468:3268-3277.
  • [45]Berbari EF, Hanssen AD, Duffy MC, Steckelberg JM, Ilstrup DM, Harmsen WS, Osmon DR: Risk factors for prosthetic joint infection: case–control study. Clin Infect Dis 1998, 27:1247-1254.
  • [46]Trampuz A, Zimmerli W: New strategies for the treatment of infections associated with prosthetic joints. Curr Opin Investig Drugs 2005, 6:185-190.
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