Impact of ABO blood group on the prognosis of patients undergoing surgery for esophageal cancer

BMC Surgery

Minxin Shi³  Qiang Wang³  Yixin Zhang³  Ziang Cao²  Tianlong Ling²  Qi He¹  Min Wei¹  Zhiwei Wang²  Lei Liu³  Wei Wang³ 

[1] Department of Breast, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University, Shanghai, China;Department of Thoracic Surgery, Shanghai Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China;Department of Surgery, The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China

关键词: Prognosis;    ABO blood group;    Esophageal cancer;   

Others  :  1228294
DOI  :  10.1186/s12893-015-0094-1

 received in 2014-09-03, accepted in 2015-09-23,  发布年份 2015

【 摘 要 】

Background

ABO blood type is an established prognostic factor in several malignancies, but its role in esophageal cancer (EC) is largely unknown. The aim of this study is to determine whether ABO blood group is associated with survival after esophagectomy for EC.

Methods

A total of 406 patients who underwent surgery for EC were enrolled. The associations of ABO blood group with clinical and pathological variables were assessed using chi-square test. Associations of ABO blood group with the survival were estimated using univariable and multivariable Cox proportional hazards regression models.

Results

The ABO blood group proportionally associated with the grade of EC tumor (P = 0.049). The ABO blood group status did not correlate with disease-free survival (DFS) in univariable analysis or multivariable analysis (P > 0.05). And there was no significant relationship between the ABO blood group and overall survival (OS) in univariable analysis or multivariable analysis (P > 0.05).

Conclusions

Our results suggested that no association between ABO blood group and the survival was observed in patients undergoing surgery for EC.

【 授权许可】

   
2015 Wang et al.

【 图 表 】

Fig. 1.

Fig. 2.

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