Amsterdam tool for clinical medication review: development and testing of a comprehensive tool for pharmacists and general practitioners

BMC Research Notes

Jacqueline G. Hugtenburg¹  Giel Nijpels²  Petra J. M. Elders²  Walter Cambach³  Sacha C. Hoogenboom¹  Abeer Ahmad¹  Ruth Mast¹ 

[1] Department of Clinical Pharmacology and Pharmacy and the EMGO, Institute for Health and Care Research, VU University Medical Center, Van Der Boechorststraat 7, Amsterdam, 1081 BT, The Netherlands;Department of General Practice and Elderly Care Medicine and the EMGO, Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands;Institute for Rational Drug Use, Utrecht, The Netherlands

关键词: Patients experience;    General practice;    Community pharmacy;    Tool;    Medication review;    Potentially inappropriate medicine;    Drug-related problems;   

Others  :  1232826
DOI  :  10.1186/s13104-015-1566-1

 received in 2015-06-08, accepted in 2015-10-05,  发布年份 2015

【 摘 要 】

Background

Drug-related problems are prevalent among older patients, and substantially increase the risk of morbidity, (re-)hospitalisation and mortality. To detect drug-related problems and optimize treatment primary caregivers should periodically review the medication of older patients. The aim was to develop a structured, comprehensive but practicable tool to facilitate and support the reviewing of medication of older patients with a chronic disease by pharmacists and general practitioners.

Methods

A tool facilitating clinical medication review by community pharmacists was developed on the basis of treatment guidelines, literature data on drug-related problems. For the identification of drug-related problems from the patient’s perspective, a script for structured interviews was developed. The tool was optimized by means of a Delphi method with an expert panel and testing in a trial.

Results

The medication review tool consists of a comprehensive checklist of 124 drug-related problems divided by 20 sections according to physiological systems and diseases, and includes a structured interview script for a patient interviews.

Conclusion

A structured, comprehensive and practical tool to assist pharmacists and general practitioners to perform clinical medication review including a list of potential drug-related problems in older patients with chronic disease, as well as a script for structured patient interviews, was developed.

【 授权许可】

   
2015 Mast et al.

【 参考文献 】

• [1]Strand LM, Morley PC, Cipolle RJ, et al.: Drug-related problems: their structure and function. DICP. Ann Pharmacother 1990, 24:1093-1097.
• [2]Van Mil JW, Westerlund LO, Hersberger KE, Schaefer MA: Drug-related problem classification systems. Ann Pharmacother 2005, 38:859-867.
• [3]Pharmaceutical Care Network Europe Foundation. The PCNE Classification V 6.2. 14-1-2010. http://www.pcne.org/upload/files/11_PCNE_classification_V6-2.pdf. Accessed 19 Sept 2012.
• [4]Schnipper JL, Kirwin JL, Cotugno MC: Role of pharmacist counseling in preventing adverse drug events after hospitalization. Arch Intern Med 2006, 166:565-571.
• [5]Roughead EE, Semple SJ: Medication safety in acute care in Australia: where are we now? Part 1: a review of the extent and causes of medication problems 2002–2008. Aust N Z Health Policy 2009, 6:18. BioMed Central Full Text
• [6]Spinewine A, Schmader KE, Barber N, et al.: Appropriate prescribing in elderly people:how well can it be measured and optimised? Lancet 2014, 370:173-184.
• [7]Levy HB, Marcus EL, Christen C: Beyond the beers criteria: a comparative overview of explicit criteria. Ann Pharmacother 2010, 44:1968-1975.
• [8]Samsa GP, Hanlon JT, Schmader KE, et al.: A summated score for the medication appropriateness index: development and assessment of clinimetric properties including content validity. J Clin Epidemiol 1994, 47:891-896.
• [9]Fiss T, Dreier A, Meinke C, et al.: Frequency of inappropriate drugs in primary care: analysis of a sample of immobile patients who received periodic home visits. Age Age 2011, 40:66-73.
• [10]O’Mahony D, Gallagher PF: Inappropriate prescribing in the older population: need for new criteria. Age Age 2008, 37:138-141.
• [11]De Smet PA, Denneboom W, Kramers C, et al.: A composite screening tool for medication reviews of outpatients: general issues with specific examples. Drug Aging 2007, 24:733-760.
• [12]Verduijn M, Leendertse A, Moeselaar A, et al.: Multidisciplinaire richtlijn Polyfarmacie bij ouderen. Huisarts Wetenschap 2013, 56:414-419.
• [13]Lowe CJ, Petty DR, Zermansky AG, et al.: Development of a method for clinical medication review by a pharmacist in general practice. Pharm World Sci 2000, 22:121-126.
• [14]O’Sullivan D, O’Mahony D, O’Connor M, et al.: The impact of a structured pharmacist intervention on the appropriateness of prescribing in older hospitalized patients. Drug Aging 2014, 31:471-481.
• [15]Clyne W, Blenkinsopp A, and Seal R. A Guide to medication review. 2008. http://www2.cff.org.br/userfiles/52%20%20CLYNE%20W%20A%20guide%20to%20medication%20review%202008.pdf. Accessed 27 Mar 2013.
• [16]Bryant L, Coster G, McCornick R: Community pharmacist perceptions of clinical medication reviews. J Prim Health Care 2010, 3:234-242.
• [17]Viktil KK, Blix HS, Moger TA, et al.: Interview of patients by pharmacists contributes significantly to the identification of drug-related problems (DRPs). Pharmacoepidemiol Drug Safe 2006, 15:667-674.
• [18]Zermansky AG, Petty DR, Raynor DK, et al.: Randomised controlled trial of clinical medication review by a pharmacist of elderly patients receiving repeat prescriptions in general practice. BMJ 2001, 323:1340.
• [19]Poos MJJC and Gommer AM. Elderly. Ranking of diseases and disorders, prevalence, Nationaal Kompas Volksgezondheid (RIVM). 2014. http://www.nationaalkompas.nl/gezondheid-en-ziekte/ziekten-enaandoeningen/ranglijsten-van-ziekten-en-aandoeningen/. Accessed 3 Feb 2012.
• [20]Stichting Farmaceutische Kerngetallen. Data en Feiten 2011. 2011. http://www.sfk.nl/nieuws-publicaties/PW/2011/data-en-feiten-2011-gereed. Accessed 3 Feb 2012.
• [21]Nederlands Huisartsen Genootschap. NHG Richtlijnen. 2015. https://www.nhg.org/nhg-standaarden. Accessed 10 October 2011.
• [22]Fulton MM, Riley Allen E: Polypharmacy in the elderly: a literature review. J Am Acad Nurs Pract 2005, 17:123-132.
• [23]Hajjar ER, Cafiero AC, Hanlon JT: Polypharmacy in elderly patients. Am J Geriatr Pharmacother 2007, 5:345-351.
• [24]Kongkaew C, Noyce PR, Ashcroft DM: Hospital admissions associated with adverse drug reactions: a systematic review of prospective observational studies. Ann Pharmacother 2008, 42:1017-1025.
• [25]Garcia-Caballos M, Ramos-Diaz F, Jimenez-Moleon JJ, et al.: Drug-related problems in older people after hospital discharge and interventions to reduce them. Age Age 2010, 39:430-438.
• [26]Ahmad A, Nijpels G, Dekker JM, et al.: Effect of a pharmacist medication review in elderly patients discharged from the hospital. Arch Intern Med 2012, 172:1346-1347.
• [27]Ahmad A, Hugtenburg J, Welschen LM, et al.: Effect of medication review and cognitive behaviour treatment by community pharmacists of patients discharged from the hospital on drug related problems and compliance: design of a randomized controlled trial. BMC Public Health 2010, 10:133. BioMed Central Full Text
• [28]Gallagher P, Ryan C, Byrne S, et al.: STOPP (Screening Tool of Older Person’s Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation. Int J Clin Pharmacol Ther 2008, 46:72-83.
• [29]Buurma H, Bouvy ML, De Smet PAGM, et al.: Prevalence and determinants of pharmacy shopping behaviour. J Clin Pharm Ther 2008, 33:17-23.
• [30]Leikola SN, Tuomainen L, Ovaskainen H, et al.: Continuing education course to attain collaborative comprehensive medication review competencies. Am J Pharm Educ 2009, 73:108.