Cutaneous squamous cell carcinoma (SCC) arising in stump of amputated finger in a patient with resected glossal SCC

BMC Research Notes

Hisatoshi Baba²  Hiroshi Itoh¹  Mitsuo Yoshimura²  Shuji Watanabe²  Daisuke Sugita²  Kohei Negoro²  Hideaki Nakajima²  Tsuyoshi Miyazaki²  Kenzo Uchida² 

[1] Tumor Pathology, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki 23-3, Eiheiji, Fukui, 910-1193, Japan;Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki 23-3, Eiheiji, Fukui, 910-1193, Japan

关键词: Double cancer;    Glossal tumor;    Finger amputation stump;    Squamous cell carcinoma;   

Others  :  1165368
DOI  :  10.1186/1756-0500-5-595

 received in 2012-06-12, accepted in 2012-10-24,  发布年份 2012

【 摘 要 】

Background

Cutaneous squamous cell carcinoma (SCC) of the hands and fingers are sometimes locally aggressive; with higher rates of regional metastasis than other cutaneous SCC, although distant metastasis is rare.

Case presentation

We present the case of a 62–year-old Japanese man with double cancers: a tongue SCC and a cutaneous SCC. Swelling of the finger lesion developed gradually around the entire remaining middle finger after accidental amputation at the proximal interphalangeal joint. Histopathological examination of the tumor on the stump of the amputated finger indicated a well-differentiated SCC. The past history indicated surgery for SCC of the tongue 3 years earlier; with histopathology of moderately-differentiated SCC.

Conclusion

Since dedifferentiation is unlikely in metastatic tumors, the cutaneous SCC of the finger is unlikely to have originated from the tongue SCC. Alternatively, the double cancer may be two unrelated lesions or the tongue tumor could have originated from the cutaneous SCC.

【 授权许可】

   
2012 Uchida et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

【 参考文献 】

• [1]Barr LH, Menard JW: Marjolin's ulcer. The LSU experience. Cancer 1983, 52:173-175.
• [2]Davies MS, Nicholson AG, Southern S, Moss AH: Squamous cell carcinoma arising in a traumatically induced epidermal cyst. Injury 1994, 25:116-117.
• [3]Phillips TJ, Salman SM, Bhawan J, Rogers GS: Burn scar carcinoma. Diagnosis and management. Dermatol Surg 1998, 24:561-565.
• [4]Bostwick J 3rd, Pendergrast WJ Jr, Vasconez LO: Marjolin’s ulcer: an immunologically privileged tumor? Plast Reconstr Surg 1976, 57:66-69.
• [5]Schiavon M, Mazzoleni F, Chiarelli A, Matano P: Squamous cell carcinoma of the hand: fifty-five case reports. J Hand Surg Am 1988, 13:401-404.
• [6]Guitart J, Bergfeld WF, Tuthill RJ, Tubbs RR, Zienowicz R, Fleegler EJ: Squamous cell carcinoma of the nail bed: a clinicopathological study of 12 cases. Br J Dermatol 1990, 123:215-222.
• [7]Ryan RF, Litwin MS, Krementz ET: A new concept in the management of Marjolin's ulcers. Ann Surg 1998, 193:598-605.
• [8]Bozkurt M, Kapi E, Kuvat SV, Ozekinci S: Current concepts in the management of Marjolin's ulcers: outcomes from a standardized treatment protocol in 16 cases. J Burn Care Res 2010, 31:776-780.
• [9]Wu KK, Guise ER: Metastatic tumors of the hand: a report of six cases. J Hand Surg Am 1978, 3:271-276.
• [10]Baran R, Tosti A: Metastatic carcinoma to the terminal phalanx of the big toe: report of two cases and review of the literature. J Am Acad Dermatol 1994, 31:259-263.
• [11]Bunkis J, Mehrhof AI, Stayman JW 3rd: Radiation-induced carcinoma of the hand. J Hand Surg Am 1981, 6:384-387.
• [12]Mohanty S, Federowicz TE, Ueharra H: Metastatic lesions of the fingers. Surgery 1968, 64:411-415.
• [13]Pitman KT, Johnson JT: Skin metastases from head and neck squamous cell carcinoma: incidence and impact. Head Neck 1999, 21:560-565.
• [14]Yoskovitch A, Hier MP, Okrainec A, Black MJ, Rochon L: Skin metastases in squamous cell carcinoma of the head and neck. Otolaryngol Head Neck Surg 2001, 124:248-252.
• [15]Lifeso RM, Rooney RJ, el-Shaker M: Post-traumatic squamous-cell carcinoma. J Bone Joint Surg Am 1990, 72:12-18.
• [16]Stromberg BV, Keiter JE, Wray RC, Weeks PM: Scar carcinoma: prognosis and treatment. South Med J 1977, 70:821-822.