Integrating stages of change models to cast new vision on interventions to improve global retinoblastoma and childhood cancer outcomes

BMC Public Health

Catherine G Lam¹  Christina L Heminger²  Meaghann S Weaver² 

[1] International Outreach Program, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, MS 721, Memphis, TN 38105, USA;Milken Institute School of Public Health, The George Washington University, 2175 K Street NW, Washington, District of Columbia 20037, USA

关键词: Social efficacy;    Treatment barriers;    Diagnostic barriers;    Interventions;    Resource-limited settings;    Stages of change model;    Pediatric oncology;    Retinoblastoma;   

Others  :  1127089
DOI  :  10.1186/1471-2458-14-944

 received in 2013-12-23, accepted in 2014-09-09,  发布年份 2014

【 摘 要 】

Background

Retinoblastoma, the most common intraocular tumor globally, represents a curable cancer when diagnosed early and treated promptly. Delay to diagnosis, lag time prior to treatment initiation, and abandonment of treatment including upfront treatment refusal, represent stark causes of high retinoblastoma mortality rates in low- and middle- income settings, particularly regions in Africa. While a health delivery-based approach has been a historic focus of retinoblastoma treatments globally and is essential to quality care, this is necessary but not adequate. Retinoblastoma is a compelling disease model to illustrate the potential insights afforded in theory-informed approaches to improve outcomes that integrate public health and oncology perspectives, prioritizing both health service delivery and social efficacy for cure.

Discussion

Given that barriers to appropriate and timely diagnosis and treatment represent main contributors to mortality in children with retinoblastoma in resource-limited settings such as certain areas in Africa, an important priority is to overcome barriers to cure that may be predominantly socially influenced, alongside health delivery-based improvements. While Stages of Change models have been effectively utilized in cancer screening programs within settings of economic and cultural barriers, this application of health behavior theory has been limited to cancer screening rather than a comprehensive framework for treatment completion. Using retinoblastoma as a case example, we propose applying stage-based intervention models in critical stages of care, such as the Precaution Adoption Process Model to decrease delay to diagnosis and a Transtheoretical Model to increase treatment completion rates in resource-limited settings.

Summary

Stage-based theories recognize that improved cure and survival outcomes will require supportive strategies to progress households, communities, and social and economic institutions from being unaware and unengaged to committed and sustained in their respective roles. Applying a stage-based model lens to programmatic interventions in resource-limited settings has potential for visible improvement in outcomes for children with retinoblastoma and other cancers.

【 授权许可】

   
2014 Weaver et al.; licensee BioMed Central Ltd.

【 图 表 】

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