Comfort, safety and quality of upper gastrointestinal endoscopy after 2 hours fasting: a randomized controlled trial

BMC Gastroenterology

Fernando Fornari¹  Iran Moraes²  Nilton Maiolini Bonadeo²  Marcio Lubini²  Angélica Terezinha Koeppe² 

[1]School of Medicine, Programa de Pós-Graduação: Ciências em Gastroenterologia e Hepatologia, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2400, 2° andar, 90035-001, Porto Alegre-RS, Brazil

[2]Unidade de Endoscopia Digestiva, Hospital São Vicente de Paulo (HSVP), Passo Fundo-RS, Brazil

关键词: Upper GI endoscopy;    Comfort;    Short fasting;    Clear liquids;   

Others  :  857485
DOI  :  10.1186/1471-230X-13-158

 received in 2013-04-06, accepted in 2013-11-05,  发布年份 2013

【 摘 要 】

Background

Upper gastrointestinal endoscopy has been performed after fasting 8 or more hours, which can be harmful to the patients. We assessed comfort, safety and quality of endoscopy under moderate sedation after 2 hours fasting for clear liquids.

Methods

In this clinical trial, patients referred for elective endoscopy were randomly assigned to a fasting period of 8 hours (F8) or a shorter fasting (F2), in which 200 ml of clear liquids were ingested 2 hours before the procedure. Endoscopists blinded to patients fasting status carried out the endoscopies. Comfort was rated by the patients, whereas safety and quality were determined by the endoscopists.

Results

Ninety-eight patients were studied (aging 48.5 ± 16.5 years, 60% women): 50 patients (51%) in F2 and 48 in F8. Comfort was higher in F2 than F8 in regard to anxiety (8% vs. 25%; P = 0.029), general discomfort (18% vs. 42%; P = 0.010), hunger (44% vs. 67%; P = 0.024), and weakness (22% vs. 42%; P = 0.034). Regurgitation of gastric contents into the esophagus after endoscopic intubation did not differ between F2 and F8 (26% vs. 19%; P = 0.471). There was no case of pulmonary aspiration. Gastric mucosal visibility was normal in most patients either in F2 or F8 (96% vs. 98%; P = 0.999).

Conclusions

Elective upper GI endoscopy after 2 hours fasting for clear liquids was more comfortable and equally safe compared to conventional fasting. This preparation might be cautiously applied for patients in regular clinical conditions referred for elective endoscopy.

Trial registration

SAMMPRIS ClinicalTrial.gov number, NCT01492296

【 授权许可】

   
2013 Koeppe et al.; licensee BioMed Central Ltd.

【 图 表 】

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