Classification tree analysis to enhance targeting for follow-up exam of colorectal cancer screening

BMC Cancer

Yoshiki Ishikawa²  Ying-Fang Zheng⁴  Hiromu Nishiuchi³  Takeo Suda¹  Tadahiko Hasumi¹  Hiroshi Saito⁵ 

[1] Committee for Colorectal Cancer Screening of Omiya Medical Association, 2-107, Onari-cho, Kitaku, Saitama City, Saitama 331-8689, Japan

[2] Cancer Scan, 1-18-1-6B, Dogenzaka, Shibuya-ku, Tokyo 150-0043, Japan

[3] DataScience Research Institute, 3-10-41-2 F, Minami-Aoyama, Minato-ku, Tokyo 107-0062, Japan

[4] Epidemiology Research Division Epidemiology Data Center, Japan Clinical Research Support Unit, Yushima D&A Bldg. 3 F 1-10-5 Yushima, Bunkyo-ku, Tokyo 113-0034, Japan

[5] Screening Assessment & Management Division, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan

关键词: Classification tree analysis;    Diagnostic examination;    Patient compliance;    Early detection of cancer;    Occult blood;    Colorectal neoplasms;   

Others  :  1079522
DOI  :  10.1186/1471-2407-13-470

 received in 2012-10-16, accepted in 2013-09-20,  发布年份 2013

【 摘 要 】

Background

Follow-up rate after a fecal occult blood test (FOBT) is low worldwide. In order to increase the follow-up rate, segmentation of the target population has been proposed as a promising strategy, because an intervention can then be tailored toward specific subgroups of the population rather than using one type of intervention for all groups. The aim of this study is to identify subgroups that share the same patterns of characteristics related to follow-up exams after FOBT.

Methods

The study sample consisted of 143 patients aged 50–69 years who were requested to undergo follow-up exams after FOBT. A classification tree analysis was performed, using the follow-up rate as a dependent variable and sociodemographic variables, psychological variables, past FOBT and follow-up exam, family history of colorectal cancer (CRC), and history of bowel disease as predictive variables.

Results

The follow-up rate in 143 participants was 74.1% (n = 106). A classification tree analysis identified four subgroups as follows; (1) subgroup with a high degree of fear of CRC, unemployed and with a history of bowel disease (n = 24, 100.0% follow-up rate), (2) subgroup with a high degree of fear of CRC, unemployed and with no history of bowel disease (n = 17, 82.4% follow-up rate), (3) subgroup with a high degree of fear of CRC and employed (n = 24, 66.7% follow-up rate), and (4) subgroup with a low degree of fear of CRC (n = 78, 66.7% follow-up rate).

Conclusion

The identification of four subgroups with a diverse range of follow-up rates for CRC screening indicates the direction to take in future development of an effective tailored intervention strategy.

【 授权许可】

   
2013 Ishikawa et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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