Unified frame of reference improves inter-subject variability of seismocardiograms

BioMedical Engineering OnLine

Mikko Paukkunen³  Petteri Parkkila³  Raimo Kettunen¹  Raimo Sepponen² 

[1] School of Medicine, University of Eastern Finland, Kuopio, Finland

[2] Health Factory, Aalto University, Helsinki, 00076, Finland

[3] Department of Electrical Engineering and Automation, Aalto University, Helsinki, 00076, Finland

关键词: Frame of reference;    Inter-subject variability;    Three-dimensional;    Aaccelerometer;    Ballistocardiography;    Seismocardiography;   

Others  :  1137087
DOI  :  10.1186/s12938-015-0013-9

 received in 2014-08-08, accepted in 2015-02-10,  发布年份 2015

【 摘 要 】

Background

Seismocardiography is the noninvasive measurement of cardiac vibrations transmitted to the chest wall by the heart during its movement. While most applications for seismocardiography are based on unidirectional acceleration measurement, several studies have highlighted the importance of three-dimensional measurements in cardiac vibration studies. One of the main challenges in using three-dimensional measurements in seismocardiography is the significant inter-subject variability of waveforms. This study investigates the feasibility of using a unified frame of reference to improve the inter-subject variability of seismocardiographic waveforms.

Methods

Three-dimensional seismocardiography signals were acquired from ten healthy subjects to test the feasibility of the present method for improving inter-subject variability of three-dimensional seismocardiograms. The first frame of reference candidate was the orientation of the line connecting the points representing mitral valve closure and aortic valve opening in seismocardiograms. The second candidate was the orientation of the line connecting the two most distant points in the three dimensional seismocardiogram. The unification of the frame of reference was performed by rotating each subject’s three-dimensional seismocardiograms so that the lines connecting the desired features were parallel between subjects.

Results

The morphology of the three-dimensional seismocardiograms varied strongly from subject to subject. Fixing the frame of reference to the line connecting the MC and AO peaks enhanced the correlation between the subjects in the y axis from 0.42 ± 0.30 to 0.83 ± 0.14. The mean correlation calculated from all axes increased from 0.56 ± 0.26 to 0.71 ± 0.24 using the line connecting the mitral valve closure and aortic valve opening as the frame of reference. When the line connecting the two most distant points was used as a frame of reference, the correlation improved to 0.60 ± 0.22.

Conclusions

The results indicate that using a unified frame of reference is a promising method for improving the inter-subject variability of three-dimensional seismocardiograms. Also, it is observed that three-dimensional seismocardiograms seem to have latent inter-subject similarities, which are feasible to be revealed. Because the projections of the cardiac vibrations on the measurement axes differ significantly, it seems obligatory to use three-dimensional measurements when seismocardiogram analysis is based on waveform morphology.

【 授权许可】

   
2015 Paukkunen et al.; licensee BioMed Central.

【 图 表 】

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【 参考文献 】

• [1]Salerno D, Zanetti J: Seismocardiography: a new technique for recording cardiac vibrations. Concept, method, and initial observations. J Cardiovasc Technol 1990, 9((2):111-118.
• [2]Gordon J: Certain molar movements of the human body produced by the circulation of the blood. J Anat Physiol 1877, 11(Pt 3):533-536.
• [3]Bozhenko BS: Seismocardiography--a new method in the study of functional conditions of the heart. Ter Arkh 1961, 33:55-64.
• [4]Baevsky R, Egorov A, Kazarian L: Metodika seismokardiografii. Kardiologia 1964, 18:87-89.
• [5]Dinh A: Heart activity monitoring on Smartphone. Int Proc Chem Biol Environ Eng 2011, 11(9):45-49.
• [6]Korzeniowska-Kubacka I, Bilińska M, Piotrowicz R: Usefulness of seismocardiography for the diagnosis of ischemia in patients with coronary artery disease. Ann Noninvasive Electrocardiol 2005, 10(3):281-287.
• [7]Wick C, Su J, McClellan J, Brand O, Bhatti P, Buice A, et al.: A system for seismocardiography-based identification of quiescent heart phases: implications for cardiac imaging. IEEE Trans Inf Technol Biomed 2012, 16(5):869-877.
• [8]Tavakolian K, Khosrow-Khavar F, Kajbafzadeh B, Marzencki M, Blaber A, Kaminska B: Precordial acceleration signals improve the performance of diastolic timed vibrations. Med Eng Phys 2013, 35(8):1133-1140.
• [9]Becker M, Roehl A, Siekmann U, Koch A, de la Fuente M, Roissant R, et al: Simplified detection of myocardial ischemia by seismocardiography. Herz 2013, [Epub ahead of print]:1–7.
• [10]Migeotte P, De Ridder S, Tank J, Nathalie Pattyn, I I Funtova, Roman M Baevsky, et al.: Three dimensional ballisto-and seismo-cardiography: HIJ wave amplitudes are poorly correlated to maximal systolic force vector. In Proceedings of the Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE: 28 August - 1 September 2012; San Diego, California, USA. 2012.
• [11]McKay WPS, Gregson PH, McKay BWS, Militzer J: Sternal acceleration ballistocardiography and arterial pressure wave analysis to determine stroke volume. Clin Invest Med 1999, 22(1):4-14.
• [12]De Ridder S, Migeotte P F, Neyt X, Pattyn N and Prisk G: Three-dimensional ballistocardiography in microgravity: A review of past research. In Proceedings of the Engineering in Medicine and Biology Society,EMBC, 2011 Annual International Conference of the IEEE: 30 August - 3 September 2011; Boston, Massachusetts, USA. 2011.
• [13]Migeotte P, Tank J, Pattyn N, Funtova I, Baevsky R, Neyt X, et al.: Three dimensional ballistocardiography: methodology and results from microgravity and dry immersion. In Proceedings of the Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE: 2011.
• [14]Castiglioni P, Faini A, Parati G and Di Rienzo M: Wearable seismocardiography. In Proceedings of the Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE: 22–26 August 2007; Lyon, France. 2007.
• [15]Pandia K, Ravindran S, Kovacs G T, Giovangrandi L and Cole R: Chest-accelerometry for hemodynamic trending during valsalva-recovery. In Proceedings of the Applied Sciences in Biomedical and Communication Technologies (ISABEL), 2010 3rd International Symposium On: 2010.
• [16]Di Rienzo M, Meriggi P, Vaini E, Castiglioni P and Rizzo F: 24 h seismocardiogram monitoring in ambulant subjects. In Proceedings of the Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE: 2012.
• [17]Paukkunen M, Linnavuo M, Haukilehto H, Sepponen R: A system for detection of three-dimensional precordial vibrations. IJMTIE 2012, 2(1):52-66.
• [18]Wiens A, Etemadi M, Roy S, Klein L, Inan O: Towards Continuous, Non-Invasive Assessment of Ventricular Function and Hemodynamics: Wearable Ballistocardiography. IEEE Journal of Biomedical and Health Informatics 2014, PP(99):1.
• [19]Tavakolian K, Vaseghi A, Kaminska B: Improvement of ballistocardiogram processing by inclusion of respiration information. Physiol Meas 2008, 29(7):771-778.
• [20]Pandia K, Inan OT, Kovacs GTA, Giovangrandi L: Extracting respiratory information from seismocardiogram signals acquired on the chest using a miniature accelerometer. Physiol Meas 2012, 33(10):1643-1660.
• [21]Pan J, Tompkins WJ: A real-time QRS detection algorithm. Biomedical Engineering, IEEE Transactions on 1985, (3):230–236.
• [22]Crow RS, Hannan P, Jacobs D, Hedquist L, Salerno DM: Relationship between seismocardiogram and echocardiogram for events in the cardiac cycle. Am J Noninvasive Cardiol 1994, 8(1):39-46.
• [23]Tavakolian K, Ngai B, Blaber AP and Kaminska B: Infrasonic cardiac signals: Complementary windows to cardiovascular dynamics. In Proceedings of the Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE: Boston, Massachusetts, USA. 2011.