No-boundary thinking in bioinformatics research

BioData Mining

Xiuzhen Huang²⁰  Barry Bruce⁵  Alison Buchan¹¹  Clare Bates Congdon¹⁹  Carole L Cramer⁷  Steven F Jennings¹⁸  Hongmei Jiang¹⁷  Zenglu Li²²  Gail McClure³  Rick McMullen¹⁰  Jason H Moore²  Bindu Nanduri¹  Joan Peckham¹⁵  Andy Perkins⁶  Shawn W Polson¹³  Bhanu Rekepalli¹⁴  Saeed Salem¹²  Jennifer Specker⁹  Donald Wunsch¹⁶  Donghai Xiong⁴  Shuzhong Zhang⁸  Zhongming Zhao²¹ 

[1] Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Jackson, MS 39762, USA

[2] The Geisel School of Medicine, Dartmouth College, Lebanon, NH 03756, USA

[3] Arkansas Science & Technology Authority, Arkansas NSF EPSCoR, Little Rock, AR 72201, USA

[4] Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI 53223, USA

[5] Sustainable Energy & Education Research Center, University of Tennessee at Knoxville, Knoxville, TN 37996, USA

[6] Department of Computer Science and Engineering, Mississippi State University, Jackson, MS 39762, USA

[7] Arkansas Biosciences Institute, Department of Biological Sciences, Arkansas State University, Jonesboro, AR 72467, USA

[8] Department of Industrial and Systems Engineering, University of Minnesota, Minneapolis, MN 55455, USA

[9] Graduate School of Oceanography, University of Rhode Island, Narragansett, RI 02882, USA

[10] Arkansas High Performance Computing Center, University of Arkansas at Fayetteville, Fayetteville, AR 72701, USA

[11] Department of Microbiology, University of Tennessee, Knoxville, TN 37996, USA

[12] Department of Computer Science, North Dakota State University, Fargo, ND 58102, USA

[13] Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19711, USA

[14] National Institute for Computational Sciences, Department of Electrical Engineering and Computer Science, UTK and ORNL, Oak Ridge, TN 37832, USA

[15] Department of Computer Science and Statistics, University of Rhode Island, Kingston, RI 02881, USA

[16] Department of Electrical & Computer Engineering, Missouri University of Science & Technology, Rolla, MO 65409, USA

[17] Department of Statistics, Northwestern University, Evanston, IL 60208, USA

[18] Department of Information Science, University of Arkansas at Little Rock, Little Rock, AR 72204, USA

[19] Department of Computer Science, University of Southern Maine, Portland, ME 04104, USA

[20] Department of Computer Science, Arkansas State University, Jonesboro, AR 72467, USA

[21] Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN 37203, USA

[22] Center for Applied Genetic Technologies, The University of Georgia, Athens, GA 30602, USA

关键词: Human infrastructure;    No-boundary thinking;   

Others  :  797159
DOI  :  10.1186/1756-0381-6-19

 received in 2013-09-05, accepted in 2013-10-31,  发布年份 2013

【 摘 要 】

Currently there are definitions from many agencies and research societies defining “bioinformatics” as deriving knowledge from computational analysis of large volumes of biological and biomedical data. Should this be the bioinformatics research focus? We will discuss this issue in this review article. We would like to promote the idea of supporting human-infrastructure (HI) with no-boundary thinking (NT) in bioinformatics (HINT).

【 授权许可】

   
2013 Huang et al.; licensee BioMed Central Ltd.

【 参考文献 】

• [1]Hey T, Tansley S, Tolle K: The fourth paradigm: data-intensive scientific discovery. Micro Res 2009. http://fourthparadigm.org webcite
• [2]NSF leads federal efforts in Big data http://www.nsf.gov/news/news_summ.jsp?cntn_id=123607 webcite