BioMedical Engineering OnLine | |
A reconfigurable arbitrary waveform generator using PWM modulation for ultrasound research | |
Amauri A Assef1  Joaquim M Maia1  Fábio K Schneider1  Vera LSN Button2  Eduardo T Costa2  | |
[1] Electrical/Electronic Engineering Department and the Graduate School of Electrical Engineering and Applied Computer Sciences (DAELT – DAELN – CPGEI), Federal University of Technology – Paraná (UTFPR), Curitiba, PR, Brazil | |
[2] Biomedical Engineering Department of the School of Electrical and Computer Engineering (DEB/FEEC) and Biomedical Engineering Centre (CEB), University of Campinas (UNICAMP), Campinas, SP, Brazil | |
关键词: Transmit beamformer; Arbitrary waveform generator; FPGA; Ultrasound; | |
Others : 797917 DOI : 10.1186/1475-925X-12-24 |
|
received in 2012-12-17, accepted in 2013-03-12, 发布年份 2013 | |
【 摘 要 】
Background
In ultrasound imaging systems, the digital transmit beamformer is a critical module that generates accurate control over several transmission parameters. However, such transmit front-end module is not typically accessible to ultrasound researchers. To overcome this difficulty, we have been developing a compact and fully programmable digital transmit system using the pulse-width modulation (PWM) technique for generating simultaneous arbitrary waveforms, specifically designed for research purposes.
Methods
In this paper we present a reconfigurable arbitrary waveform generator (RAWG) for ultrasound research applications that exploits a high frequency PWM scheme implemented in a low-cost FPGA, taking advantage of its flexibility and parallel processing capability for independent controlling of multiple transmission parameters. The 8-channel platform consists of a FPGA-based development board including an USB 2.0 interface and an arbitrary waveform generator board with eight MD2130 beamformer source drivers for individual control of waveform, amplitude apodization, phase angle and time delay trigger.
Results
To evaluate the efficiency of our system, we used equivalent RC loads (1 kΩ and 220 pF) to produce arbitrary excitation waveforms with the Gaussian and Tukey profiles. The PWM carrier frequency was set at 160 MHz featuring high resolution while keeping a minimum time delay of 3.125 ns between pulses to enable the acoustic beam to be focused and/or steered electronically. Preliminary experimental results show that the RAWG can produce complex arbitrary pulses with amplitude over 100 Vpp and central frequency up to 20 MHz with satisfactory linearity of the amplitude apodization, as well as focusing phase adjustment capability with angular resolution of 7.5°.
Conclusions
The initial results of this study showed that the proposed research system is suitable for generating simultaneous arbitrary waveforms, providing extensive user control with direct digital access to the various transmission parameters needed to explore alternative ultrasound transmission techniques.
【 授权许可】
2013 Assef et al.; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
20140706085751557.pdf | 1269KB | download | |
Figure 10. | 56KB | Image | download |
Figure 9. | 86KB | Image | download |
Figure 8. | 79KB | Image | download |
Figure 7. | 116KB | Image | download |
Figure 6. | 70KB | Image | download |
Figure 5. | 100KB | Image | download |
Figure 4. | 59KB | Image | download |
Figure 3. | 48KB | Image | download |
Figure 2. | 63KB | Image | download |
Figure 1. | 40KB | Image | download |
【 图 表 】
Figure 1.
Figure 2.
Figure 3.
Figure 4.
Figure 5.
Figure 6.
Figure 7.
Figure 8.
Figure 9.
Figure 10.
【 参考文献 】
- [1]Thomenius KE: Evaluation of ultrasound beamformers. In Proceedings of the IEEE Ultrason. Symp. 1996, 2:1615-1622.
- [2]Basoglu C, Managuli R, York G, Kim Y: Computing requirements of modern medical diagnostic ultrasound machines. Parallel Comput. 1998, 24:1407-1431.
- [3]Tortoli P, Jensen JA: Introduction to the special issue on novel equipment for ultrasound research. IEEE Trans Ultrason Ferroelectr Freq Control 2006, 53:1705-1706.
- [4]Bassi L, Boni E, Cellai A, Dallai A, Guidi F, Ricci S, Tortoli P: A Novel Digital Ultrasound System for Experimental Research Activities. 11th EUROMICRO Conference on DSD 2008 2008, 413-417.
- [5]Wilson T, Zagzebski J, Varghese T, Chen Q, Rao M: The ultrasonix 500RP: A commercial ultrasound research interface. IEEE Trans Ultrason Ferroelectr Freq Control 2006, 53:1772-1782.
- [6]Maxim Integrated Medical Solutions Guide: Ultrasound Imaging Systems. [http://www.maximintegrated.com/solutions/guide/medical/Ultrasound.pdf webcite]
- [7]Brunner E: How ultrasound system considerations influence front-end component choice. [http://www.analog.com/library/analogdialogue/archives/36-03/ultrasound/ultrasound.pdf webcite]
- [8]Brown JA, Lockwood GR: A Low-cost, high-performance pulse generator for ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control 2002, 49:848-851.
- [9]Xu X, Yen JT, Shung KK: Low-cost bipolar pulse generator for high-frequency ultrasound applications. IEEE Trans Ultrason Ferroelectr Freq Control 2007, 54:443-447.
- [10]Ricci S, Bassi L, Boni E, Dallai A, Tortoli P: Multichannel FPGA-based arbitrary waveform generator for medical ultrasound. Electron Lett 2007, 43:1335-1336.
- [11]Sikdar S, Managuli R, Gong L, Shamdasani V, Mitake T, Hayashi T, Kim Y: A single mediaprocessor-based programmable ultrasound system. IEEE Trans Ultrason Ferroelectr Freq Control 2003, 7:64-70.
- [12]Kaczkowski PJ, Daigle RE: The Verasonics ultrasound system as a pedagogic tool in teaching wave propagation, scattering, beamforming, and signal processing concepts in physics and engineering. J Acoust Soc Am 2011, 129:2648-2648.
- [13]Daigle RE, Pflugrath L, Flynn J, Linkhart K, Kaczkowski PJ: High frame rate quantitative Doppler imaging over a wide field of view. [http://www.verasonics.com/pdf/ieee_verasonics_2009_specs.pdf webcite]
- [14]Tortoli P, Bassi L, Boni E, Dallai A, Guidi F, Ricci S: ULA-OP: an advanced open platform for ultrasound research. IEEE Trans Ultrason Ferroelectr Freq Control 2009, 56:2207-2216.
- [15]Jensen JA, Holm O, Jensen LJ, Bendsen H, Nikolov SI, Tomov BG, Munk P, Hansen M, Salomonsen K, Hansen J, Gormsen K, Pedersen HM, Gammelmark KL: Ultrasound research scanner for real-time synthetic aperture data acquisition. IEEE Trans Ultrason Ferroelectr Freq Control 2005, 52:881-891.
- [16]Ricci S, Boni E, Guidi F, Morganti T, Tortoli P: A programmable real-time system for development and test of New ultrasound investigation methods. IEEE Trans Ultrason Ferroelectr Freq Control 2006, 53:1813-1819.
- [17]Chang-Hong H, Xiao-Chen X, Cannata JM, Yen JT, Shung KK: Development of a real-time, high-frequency ultrasound digital beamformer for high-frequency linear array transducers. IEEE Trans Ultrason Ferroelectr Freq Control 2006, 53:317-323.
- [18]Boni E, Bassi L, Dallai A, Guidi F, Ramalli A, Ricci S, Housden J, Tortoli P: A reconfigurable and programmable FPGA-based system for nonstandard ultrasound methods. IEEE Trans Ultrason Ferroelectr Freq Control 2012, 59:1378-1385.
- [19]Qiu W, Yu Y, Tsang F, Sun L: A multifunctional, reconfigurable pulse generator for high-frequency ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control 2012, 59:1558-1567.
- [20]Kim GD, Yoon C, Kye SB, Lee Y, Kang J, Yoo Y, Song TK: A single FPGA-based portable ultrasound imaging system for point-of-care applications. IEEE Trans Ultrason Ferroelectr Freq Control 2012, 59:1386-1394.
- [21]Assef AA, Maia JM, Schneider FK, Costa ET, da Silveira Nantes Button VL: A Programmable FPGA-based 8-Channel Arbitrary Waveform Generator for Medical Ultrasound Research Activities. 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2012, 515-518.
- [22]Jensen JA: Linear description of ultrasound imaging systems. [http://field-ii.dk/documents/ref_jaj_1999.pdf webcite]
- [23]Cincotti G, Cardone G, Gori P, Pappalardo M: Efficient transmit beamforming in pulse-echo ultrasonic imaging. IEEE Trans Ultrason Ferroelectr Freq Control 1999, 46:1450-1458.
- [24]Hedrick WR, Hykes DL, Starchman DE: Ultrasound Physics and Instrumentation. London: Mosby, Inc.; 1995.
- [25]Thomenius KE: Recent Trends in Beamformation in Medical Ultrasound. [http://folk.ntnu.no/htorp/Undervisning/MEDT8007/notater/TrendsBeamforming.Thomenius.pdf webcite]
- [26]Supertex Inc: MD2130 High Speed Ultrasound Beamforming Source Driver. [http://www.supertex.com/pdf/datasheets/MD2130.pdf webcite]
- [27]Zhou S, Hossack JA: Dynamic-transmit focusing using time dependent focal zone and center frequency. IEEE Trans Ultrason Ferroelectr Freq Control 2003, 50:142-152.
- [28]Mamou J, Ketterling JA, Silverman RH: Chirp-coded excitation imaging with a high-frequency ultrasound annular array. IEEE Trans Ultrason Ferroelectr Freq Control 2008, 55:508-513.
- [29]Supertex Inc: MD2131 High Speed Ultrasound Beamforming Source Driver. [http://www.supertex.com/pdf/datasheets/MD2131.pdf webcite]
- [30]Huang SW, Li PC: Arbitrary waveform coded excitation using bipolar square wave pulsers in medical ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control 2006, 53:106-116.
- [31]Kennedy JE, ter Haar GR, Cranston D: High intensity focused ultrasound: surgery of the future? Br J Radiol 2003, 76:590-599.