期刊论文详细信息
BioMedical Engineering OnLine
Implementation of a portable device for real-time ECG signal analysis
Byung-Geun Lee2  Moongu Jeon3  Byoungho Kim1  Taegyun Jeon3 
[1]Broadcom Corporation, Irvine CA 92617, USA
[2]School of Mechatronics, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea
[3]School of Information and Communications, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea
关键词: Embedded device;    Feature extraction;    Myocardial ischemia;    Atrial fibrillation;    Heart disease;    Portable ECG device;   
Others  :  1084190
DOI  :  10.1186/1475-925X-13-160
 received in 2014-08-28, accepted in 2014-11-19,  发布年份 2014
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【 摘 要 】

Background

Cardiac disease is one of the main causes of catastrophic mortality. Therefore, detecting the symptoms of cardiac disease as early as possible is important for increasing the patient’s survival. In this study, a compact and effective architecture for detecting atrial fibrillation (AFib) and myocardial ischemia is proposed. We developed a portable device using this architecture, which allows real-time electrocardiogram (ECG) signal acquisition and analysis for cardiac diseases.

Methods

A noisy ECG signal was preprocessed by an analog front-end consisting of analog filters and amplifiers before it was converted into digital data. The analog front-end was minimized to reduce the size of the device and power consumption by implementing some of its functions with digital filters realized in software. With the ECG data, we detected QRS complexes based on wavelet analysis and feature extraction for morphological shape and regularity using an ARM processor. A classifier for cardiac disease was constructed based on features extracted from a training dataset using support vector machines. The classifier then categorized the ECG data into normal beats, AFib, and myocardial ischemia.

Results

A portable ECG device was implemented, and successfully acquired and processed ECG signals. The performance of this device was also verified by comparing the processed ECG data with high-quality ECG data from a public cardiac database. Because of reduced computational complexity, the ARM processor was able to process up to a thousand samples per second, and this allowed real-time acquisition and diagnosis of heart disease. Experimental results for detection of heart disease showed that the device classified AFib and ischemia with a sensitivity of 95.1% and a specificity of 95.9%.

Conclusions

Current home care and telemedicine systems have a separate device and diagnostic service system, which results in additional time and cost. Our proposed portable ECG device provides captured ECG data and suspected waveform to identify sporadic and chronic events of heart diseases. This device has been built and evaluated for high quality of signals, low computational complexity, and accurate detection.

【 授权许可】

   
2014 Jeon et al.; licensee BioMed Central Ltd.

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【 参考文献 】
  • [1]Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Blaha MJ, Dai S, Ford ES, Fox CS, Franco S, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Huffman MD, Judd SE, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Mackey RH, Magid DJ, Marcus GM, Marelli A, Matchar DB, McGuire DK, III ERM, Moy CS, et al.: Heart disease and stroke statistics–2014 update: a report from the American Heart Association. Circulation 2013, 129:e28-e292.
  • [2]Levy S, Camm AJ, Saksena S, Aliot E, Breithardt G, Crijns H, Davies W, Kay N, Prystowsky E, Sutton R, Waldo A, Wyse DG: International consensus on nomenclature and classification of atrial fibrillation. Europace 2003, 5:119-122.
  • [3]Rieta JJ, Castells F, Sánchez C, Zarzoso V, Millet J: Atrial activity extraction for atrial fibrillation analysis using blind source separation. IEEE Trans Biomed Eng 2004, 51(7):1176-1186.
  • [4]Petrutiu S, Ng J, Nijm GM, Al-Angari HM, Swiryn S, Sahakian AV: Atrial fibrillation and waveform characterization. IEEE Eng Med Biol Mag 2006, 25(6):24-30.
  • [5]Asl BM, Setarehdan SK, Mohebbi M: Support vector machine-based arrhythmia classification using reduced features of heart rate variability signal. Artif Intell Med 2008, 44:51-64.
  • [6]García J, Sörnmo L, Olmos S, Laguna P: Automatic detection of ST-T complex changes on the ECG using filtered RMS difference series: application to ambulatory ischemia monitoring. IEEE Trans Biomed Eng 2000, 47(9):1195-1201.
  • [7]Kusumoto FM: Cardiovascular Pathophysiology. Raleigh, North Carolina: Hayes Barton Press; 2004.
  • [8]Pueyo E, Sörnmo L, Laguna P: QRS slopes for detection and characterization of myocardial ischemia. IEEE Trans Biomed Eng 2008, 55(2):468-477.
  • [9]Ruud TS, Nielsen BF, Lysaker M, Sundnes J: A computationally efficient method for determining the size and location of myocardial ischemia. IEEE Trans Biomed Eng 2009, 56(2):263-272.
  • [10]Papaloukas C, Fotiadis D, Likas A, Michalis L: An ischemia detectionmethod based on artificial neural networks. Artif Intell Med 2002, 24:167-178.
  • [11]Goletsis Y, Papaloukas C, Fotiadis D, Likas A, Michalis L: Automated ischemic beat classification using genetic algorithms andmulticriteria decision analysis. IEEE Trans Biomed Eng 2004, 51:1717-1725.
  • [12]Logan B, Healey J: Robust detection of atrial fibrillation for a long term telemonitoring system. In Computers in Cardiology. IEEE 2005, 619-622.
  • [13]Exarchos T, Tsipouras M, Exarchos C, Papaloukas C, Fotiadis D, Michalis L: Amethodology for the automated creation of fuzzy expert systems for ischaemic and arrhythmic beat classification based on a set of rules obtained by a decision tree. Artif Intell Med 2007, 40:187-200.
  • [14]Kikillus N, Hammer G, Wieland S, Bolz A: Algorithm for identifying patients with paroxysmal atrial fibrillation without appearance on the ECG. Conf Proc IEEE Eng Med Biol Soc 2007, 2007:275-8.
  • [15]Dash S, Chon K, Lu S, Raeder E: Automatic real time detection of atrial fibrillation. Ann Biomed Eng 2009, 37:1701-1709.
  • [16]Park J, Lee S, Jeon M: Atrial fibrillation detection by heart rate variability in Poincare plot. Biomed Eng Online 2009, 8(38):1-12.
  • [17]Park J, Pedrycz W, Jeon M: Ischemia episode detection in ECG using kernel density estimation, support vector machine and feature selection. Biomed Eng Online 2012, 11(30):1-22.
  • [18]AliveCor Heart Monitor: iPhoneECG. [http://www.alivecor.com/ webcite]
  • [19]Everist Health: CardioDefender. [http://everisthealth.com/ webcite]
  • [20]Beurer: ME 80. [http://www.beurer.com webcite]
  • [21]HeartrHeart: EPI Life. [http://www.heartronics.com.my webcite]
  • [22]DailyCare BioMedical: ReadMyHeart. [http://www.dcbiomed.com/webls-en-us/ReadMyHeart:V2.0.html webcite]
  • [23]Cardiac Designs: ECGCheck. [http://www.ecgcheck.com/ webcite]
  • [24]Dimetek: Dicare-m1C. [http://www.dimetekus.com/Micro-Ambulatory-ECG-Recorder_p238.html webcite]
  • [25]HeartCheck: The HeartCheck PEN. [http://www.theheartcheck.com/products/pen_device.html webcite]
  • [26]REKA Health: E100 cardiac Monitor. [https://www.rekahealth.com webcite]
  • [27]SHL Telemedicine: Smartheart. [http://www.shl-telemedicine.com/portfolio/smartheart webcite]
  • [28]Mortara: ELI 10 mobile. [http://www.mortara.com webcite]
  • [29]ChoiceMMed: MD100E. [http://www.choicemmed.com/info.aspx?m=photo&id=537 webcite]
  • [30]Creative Medical: PC-80. [http://www.creative-sz.com/Easy-ECG-Monitor/Easy-ECG-Monitor-PC-80A.html webcite]
  • [31]CONTEC Medical System: ECG80A. [http://www.contecmed.com webcite]
  • [32]Baig MM, Gholamhosseini H, Connoly MJ: A comprehensive survey of wearable and wireless ECG monitoring systems for older adults. Med Biol Eng Comput 2013, 51:485-495.
  • [33]Dobrev D: Review of “Analysis and application of analog electronic circuits to biomedical instrumentation” by Robert B Northrop. Biomed Eng Online 2012, 11(29):1-7.
  • [34]Vázquez-Seisdedos CR, Neto JaE, Marañón Reyes EJ, Klautau A, Limão de Oliveira RC: New approach for T-wave end detection on electrocardiogram: performance in noisy conditions. Biomed Eng Online 2011, 10(77):1-11.
  • [35]Poungponsri S, Yu XH: An adaptive filtering approach for electrocardiogram (ECG) signal noise reduction using neural networks. Neurocomputing 2013, 117:206-213.
  • [36]Goldberger AL, Amaral LAN, Glass L, Hausdorff JM, Ivanov PC, Mark RG, Mietus JE, Moody GB, Peng CK, Stanley HE: PhysioBank, PhysioToolkit, and PhysioNet: Components of a new research resource for complex physiologic signals. Circulation 2000, 101(23):e215-e220. [Circulation Electronic Pages: http://circ.ahajournals.org/cgi/content/full/101/23/e215 PMID:1085218;doi:10.1161/01.CIR.101.23.e215 webcite]
  • [37]Chung FR: Spectral graph theory, Volume 92. USA: American Mathematical Soc.; 1997.
  • [38]Chang CC, Lin CJ: LIBSVM: A library for support vector machines. ACM Trans Intell Syst Technol 2011, 2:27:1-27:27. Software available at [http://www.csie.ntu.edu.tw/~cjlin/libsvm webcite]
  • [39]Kasmacher H, Wiese S, Lahl M: Monitoring the complexity of ventricular response in atrial fibrillation. Discrete Dyn Nat Soc 2000, 4:63-89.
  • [40]Zemaityte D, Varoneckas G, Ozeraitis E, Podlipskyte A, Valyte G, Zakarevicius L: Heart rate Poincare plots and their hemodynamic correlates: discrimination between sinus and ectopic rhythms. Biomedicine 2001, 1(2):80-89.
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