In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution

BioMedical Engineering OnLine

Hazibullah Waizy⁵  Andreas Weizbauer⁵  Christian Modrejewski⁵  Frank Witte⁵  Henning Windhagen⁵  Arne Lucas²  Marc Kieke⁴  Berend Denkena²  Peter Behrens⁴  Andrea Meyer-Lindenberg³  Friedrich-Wilhelm Bach⁶  Fritz Thorey¹ 

[1] Center for Hip, Knee and Foot Surgery, ATOS Clinic Heidelberg, Bismarckstr. 9-15, 69115 Heidelberg, Germany

[2] Institute of Production Engineering and Machine Tools (IFW), Leibnitz University of Hannover, Lise-Meitner-Str. 1, 30823 Garbsen, Germany

[3] Clinic for Small Animal Surgery and Reproduction, Centre of Clinical Veterinary Medicine, Faculty of Veterinary Medicine Ludwig-Maximilians-Universität München, Veterinärstr. 13, 80539 Munich, Germany

[4] Institute for Inorganic Chemistry, Leibniz University of Hannover, Callinstr. 9, 30167 Hannover, Germany

[5] Department of Orthopedic Surgery, Hannover Medical School, Anna-von-Borries-Str.1-7, 30625 Hannover, Germany

[6] Institute of Materials Science, Leibniz University Hannover, An der Universität 2, 30823 Garbsen, Germany

关键词: in vitro study;    Plates;    Corrosion;    Magnesium alloy;   

Others  :  798117
DOI  :  10.1186/1475-925X-11-12

 received in 2011-12-09, accepted in 2012-03-13,  发布年份 2012

【 摘 要 】

Background

In recent years magnesium alloys have been intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, the prevention of both stress shielding and removal of the implant after surgery.

Methods

ZEK100 plates were examined in this in vitro study with Hank's Balanced Salt Solution under physiological conditions with a constant laminar flow rate. After 14, 28 and 42 days of immersion the ZEK100 plates were mechanically tested via four point bending test. The surfaces of the immersed specimens were characterized by SEM, EDX and XRD.

Results

The four point bending test displayed an increased bending strength after 6 weeks immersion compared to the 2 week group and 4 week group. The characterization of the surface revealed the presence of high amounts of O, P and Ca on the surface and small Mg content. This indicates the precipitation of calcium phosphates with low solubility on the surface of the ZEK100 plates.

Conclusions

The results of the present in vitro study indicate that ZEK100 is a potential candidate for degradable orthopedic implants. Further investigations are needed to examine the degradation behavior.

【 授权许可】

   
2012 Waizy et al; licensee BioMed Central Ltd.

【 图 表 】

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