Biomolecular assembly strategies to develop potential artificial cellulosomes

Sustainable Chemical Processes

Geisa AL Gonçalves¹  Yutaro Mori¹  Noriho Kamiya² 

[1] Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744, Motooka, Nishi-Ku, Fukuoka, Japan

[2] Center for Future Chemistry, Kyushu University, 744, Motooka, Nishi-Ku, Fukuoka, Japan

关键词: Multi-enzymatic system;    Lignocellulose;    Cellulosome;    Biocatalyst;    Artificial cellulosome;   

Others  :  1082508
DOI  :  10.1186/s40508-014-0019-9

 received in 2014-04-04, accepted in 2014-09-23,  发布年份 2014

【 摘 要 】

Cellulosic biomass is a sustainable source for fuels and value-added chemicals, and is available in large quantities. One of the key challenges in biomass processing is associated with the establishment of an efficient enzymatic degradation of plant cell wall. A multi-enzymatic complex, cellulosome, was identified as a highly efficient biocatalyst for the hydrolysis of cellulosic biomass in nature. Significant progress has been achieved on cellulosome production and application since its discovery, but there is still a gap for industrial use. Artificial systems are being developed by employing various pairs of proteins and scaffolds with the objective of reconstructing this natural multi-enzymatic complex for sustainable biotechnology application.

【 授权许可】

   
2014 Gonçalves et al.; licensee Springer.

【 图 表 】

Figure 1.

Figure 2.

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