SketchBio: a scientist’s 3D interface for molecular modeling and animation

BMC Bioinformatics

Russell M¹  Patrick J Hahn¹  Peter M Thompson¹  Shawn M Waldon¹ 

[1]University of North Carolina at Chapel Hill, 27599 Chapel Hill, NC, USA

关键词: Collision detection;    Animation;    Molecular modelling;   

Others  :  1085321
DOI  :  10.1186/1471-2105-15-334

 received in 2014-04-24, accepted in 2014-09-19,  发布年份 2014

【 摘 要 】

Background

Because of the difficulties involved in learning and using 3D modeling and rendering software, many scientists hire programmers or animators to create models and animations. This both slows the discovery process and provides opportunities for miscommunication. Working with multiple collaborators, a tool was developed (based on a set of design goals) to enable them to directly construct models and animations.

Results

SketchBio is presented, a tool that incorporates state-of-the-art bimanual interaction and drop shadows to enable rapid construction of molecular structures and animations. It includes three novel features: crystal-by-example, pose-mode physics, and spring-based layout that accelerate operations common in the formation of molecular models. Design decisions and their consequences are presented, including cases where iterative design was required to produce effective approaches.

Conclusions

The design decisions, novel features, and inclusion of state-of-the-art techniques enabled SketchBio to meet all of its design goals. These features and decisions can be incorporated into existing and new tools to improve their effectiveness.

【 授权许可】

   
2014 Waldon et al.; licensee BioMed Central Ltd.

【 图 表 】

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