Alterations in regional homogeneity of resting-state brain activity in internet gaming addicts

Behavioral and Brain Functions

Guangheng Dong¹  Jie Huang¹  Xiaoxia Du² 

[1] Department of Psychology, Zhejiang Normal University, 688 of Yingbin Road, Jinhua city, Zhejiang Province, P.R.China

[2] Department of Physics, Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, P.R.China

关键词: Resting-state fMRI;    Internet gaming addiction;    Internet addiction disorder;   

Others  :  1106729
DOI  :  10.1186/1744-9081-8-41

 received in 2012-03-23, accepted in 2012-08-16,  发布年份 2012

【 摘 要 】

Backgrounds

Internet gaming addiction (IGA), as a subtype of internet addiction disorder, is rapidly becoming a prevalent mental health concern around the world. The neurobiological underpinnings of IGA should be studied to unravel the potential heterogeneity of IGA. This study investigated the brain functions in IGA patients with resting-state fMRI.

Methods

Fifteen IGA subjects and fourteen healthy controls participated in this study. Regional homogeneity (ReHo) measures were used to detect the abnormal functional integrations.

Results

Comparing to the healthy controls, IGA subjects show enhanced ReHo in brainstem, inferior parietal lobule, left posterior cerebellum, and left middle frontal gyrus. All of these regions are thought related with sensory-motor coordination. In addition, IGA subjects show decreased ReHo in temporal, occipital and parietal brain regions. These regions are thought responsible for visual and auditory functions.

Conclusions

Our results suggest that long-time online game playing enhanced the brain synchronization in sensory-motor coordination related brain regions and decreased the excitability in visual and auditory related brain regions.

【 授权许可】

   
2012 Dong et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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