A case of hypomania during nicotine cessation treatment with bupropion

Addiction Science & Clinical Practice

Karine Giasson-Gariépy¹  Didier Jutras-Aswad¹ 

[1] Department of Psychiatry, Université de Montréal, Montreal, Quebec, Canada

关键词: Venlafaxine;    Hypomania;    Antidepressant;    Bupropion;    Smoking cessation;    Nicotine;   

Others  :  789277
DOI  :  10.1186/1940-0640-8-22

 received in 2013-07-12, accepted in 2013-12-18,  发布年份 2013

【 摘 要 】

Antidepressants can increase the spontaneous risk of hypomania or mania when used for treatment in affective disorders. When prescribed as an antidepressant, bupropion is generally considered to have a lower relative risk of inducing mood shifts. We describe the case of a 67-year-old man known for dysthymic disorder in remission on quetiapine and venlafaxine who experienced a first lifetime episode of hypomania with the introduction of bupropion SR for smoking cessation. To the best of our knowledge, this is the first case report of bupropion-induced mood shift when used specifically for nicotine cessation in a nonbipolar patient. This case highlights the need for clinicians who prescribe bupropion for smoking cessation to perform regular and systematic mood follow-ups during treatment. These follow-ups could even be more important when bupropion is selected to quit smoking in a patient already taking an antidepressant.

【 授权许可】

   
2013 Giasson-Gariépy and Jutras-Aswad; licensee BioMed Central Ltd.Jutras-Aswad

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