Benzimidazole resistance of sheep nematodes in Norway confirmed through controlled efficacy test

Acta Veterinaria Scandinavica

Atle V Meling Domke²  Christophe Chartier¹  Bjørn Gjerde³  Snorre Stuen² 

[1] LUNAM Université, Oniris, Nantes-Atlantic College of veterinary medicine and food sciences and engineering, UMR BioEpAR, Nantes, F-44307, France

[2] Norwegian School of Veterinary Science, Sandnes, Norway

[3] Norwegian School of Veterinary Science, Oslo, Norway

关键词: Sheep;    Controlled efficacy test;    FECRT;    Anthelmintic resistance;    Benzimidazole;   

Others  :  789452
DOI  :  10.1186/1751-0147-54-48

 received in 2012-06-08, accepted in 2012-08-20,  发布年份 2012

【 摘 要 】

Background

Resistance against benzimidazoles (BZ) has recently been detected in Norwegian sheep flocks through a large scale prevalence survey based on the faecal egg count reduction test (FECRT). The use of this test in combination with bulk larval culture only gives an indication of which gastrointestinal nematodes genera that are involved and these results have to be confirmed by a controlled efficacy test (CET) to get accurate information about resistant nematodes populations at species level. A CET was therefore performed with larvae from two flocks where BZ resistance was previously detected through FECRT.

Results

The latter test confirmed the previous results in both flocks. In flock A, the BZ resistant nematode population consisted solely of Haemonchus contortus, whereas H. contortus and Teladorsagia circumcincta comprised the resistant worm population in flock B.

Conclusions

Some discrepancies that have been recorded between FECRT and CET results regarding time for post-treatment coproscopical examination and a temporary suppression of faecal egg excretion are discussed.

【 授权许可】

   
2012 Domke et al.; licensee BioMed Central Ltd.

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