Secretory pathway of cellulase: a mini-review

Biotechnology for Biofuels

Shaomin Yan²  Guang Wu¹ 

[1] DreamSciTech, Apt 207, Zhencaili 26, Zhujiang Road, Hexi District, Tianjin, 300222, China

[2] State Key Laboratory of Non-food Biomass Enzyme Technology, National Engineering Research Center for Non-food Biorefinery, Guangxi Key Laboratory of Biorefinery, Guangxi Academy of Sciences, 98 Daling Road, Nanning, Guangxi 530007, China

关键词: UniProtKB;    Secretory mechanism;    Subcellular location;    Secretory pathway;    Cellulase;   

Others  :  794423
DOI  :  10.1186/1754-6834-6-177

 received in 2013-10-02, accepted in 2013-11-19,  发布年份 2013

【 摘 要 】

Cellulase plays an important role in modern industry and holds great potential in biofuel production. Many different types of organisms produce cellulase, which go through secretory pathways to reach the extracellular space, where enzymatic reactions take place. Secretory pathways in various cells have been the focus of many research fields; however, there are few studies on secretory pathways of cellulases in the literature. It is therefore necessary and important to review the current knowledge on the secretory pathways of cellulases. In this mini-review, we address the subcellular locations of cellulases in different organisms, discuss the secretory pathways of cellulases in different organisms, and examine the secretory mechanisms of cellulases. These sections start with a description of general secreted proteins, advance to the situation of cellulases, and end with the knowledge of cellulases, as documented in UniProt Knowledgebase (UniProtKB). Finally, gaps in existing knowledge are highlighted, which may shed light on future studies for biofuel engineering.

【 授权许可】

   
2013 Yan and Wu; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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