Respiratory syncytial virus outbreak in neonatal intensive care unit: Impact of infection control measures plus palivizumab use

Antimicrobial Resistance and Infection Control

Camila de A Silva¹  Lívio Dias¹  Sandra R Baltieri¹  Tatiane T Rodrigues²  Neusa Brandolise Takagi¹  Rosana Richtmann² 

[1] Infection Control, Hospital e Maternidade Santa Joana, Rua do Paraíso 432, São Paulo, SP, 04103-000, Brazil

[2] Neonatology, Hospital e Maternidade Santa Joana, Rua do Paraíso 432, São Paulo, SP, 04103-000, Brazil

关键词: Neonatal intensive care;    Palivizumab;    Outbreak;    Respiratory syncytial virus;   

Others  :  791268
DOI  :  10.1186/2047-2994-1-16

 received in 2012-01-31, accepted in 2012-05-02,  发布年份 2012

【 摘 要 】

Background

The occurrence of a respiratory syncytial virus (RSV) outbreak in a Neonatal Intensive Care Unit (NICU) is related to unfavorable outcomes, as this infection can lead to respiratory distress and death in premature in infants. Report the successful control of an outbreak that occurred in April 2010 in a NICU.

Methods

After the index case, of 18 premature infants placed in the same room 10 infants were infected. Of those 10, 6 developed mild to moderate respiratory symptoms, 4 persisted asymptomatic and no death occurred. Contact and respiratory precautions were rapidly initiated, the infants were cohorted in 3 different rooms and palivizumab was administered to all contacts.

Results

The outbreak was controlled and no new cases were subsequently indentified.

Conclusion

Standard infection control measures plus palivizumab prophylaxis were efficient in rapid control of the outbreak.

【 授权许可】

   
2012 Silva et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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