| Sustainable Chemical Processes | |
| Novel perspectives for evolving enzyme cocktails for lignocellulose hydrolysis in biorefineries | |
| Saritha Mohanram1  Dolamani Amat1  Jairam Choudhary1  Anju Arora1  Lata Nain1  | |
| [1] Division of Microbiology, Indian Agricultural Research Institute, New Delhi 110 012, India | |
| 关键词: Enzymatic saccharification; Bioprospecting; Hemicellulase; Cellulase; Bioethanol; Lignocellulose; | |
| Others : 789179 DOI : 10.1186/2043-7129-1-15 |
|
| received in 2013-05-10, accepted in 2013-07-17, 发布年份 2013 | |
PDF
|
|
【 摘 要 】
The unstable and uncertain availability of petroleum sources as well as rising cost of fuels have shifted global efforts to utilize renewable resources for the production of greener energy and a replacement which can also meet the high energy demand of the world. Bioenergy routes suggest that atmospheric carbon can be cycled through biofuels in carefully designed systems for sustainability. Significant potential exists for bioconversion of biomass, the most abundant and also the most renewable biomaterial on our planet. However, the requirements of enzyme complexes which act synergistically to unlock and saccharify polysaccharides from the lignocellulose complex to fermentable sugars incur major costs in the overall process and present a great challenge. Currently available cellulase preparations are subject to tight induction and regulation systems and also suffer inhibition from various end products. Therefore, more potent and efficient enzyme preparations need to be developed for the enzymatic saccharification process to be more economical. Approaches like enzyme engineering, reconstitution of enzyme mixtures and bioprospecting for superior enzymes are gaining importance. The current scenario, however, also warrants the need for research and development of integrated biomass production and conversion systems.
【 授权许可】
2013 Mohanram et al.; licensee Chemistry Central Ltd.
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| 20140704155404951.pdf | 365KB | ||
| Figure 1. | 66KB | Image |
【 图 表 】
Figure 1.
【 参考文献 】
- [1]FAO: Biofuels and agriculture – a technical overview. Rome, Italy: FAO corporate document repository. Electronic Publishing Policy and Support Branch, FAO; 2008:10-22. [The state of food and agriculture 2008: Biofuels: prospects, risks and opportunities]
- [2]Bringezu S, Schütz H, O´Brien M, Kauppi L, Howarth RW, McNeely J: Towards sustainable production and use of resources: Assessing biofuels. UNEP; 2009. http://www.unep.org/PDF/Assessing_Biofuels.pdf webcite
- [3]Sukumaran RK, Surender VJ, Sindhu R, Binod P, Janu KU, Sajna KV, Rajasree KP, Pandey A: Lignocellulosic ethanol in India: Prospects, challenges and feedstock availability. Bioresour Technol 2010, 101:4826-4833.
- [4]Government of India: Report of the Committee on the Development of Biofuel. New Delhi: Planning Commission; 2003. http://planningcommission.nic.in/reports/genrep/cmtt_bio.pdf webcite (accessed on 20/09/2012)
- [5]Sánchez OJ, Cardona CA: Trends in biological production of fuel ethanol from different feedstocks. Bioresour Technol 2008, 99:5270-5295.
- [6]Claassen PAM, van Lier JB, Contreras LAM, van Niel EWJ, Sijtsma L, Stams AJM, de Vries SS, Weusthuis RA: Utilisation of biomass for the supply of energy carriers. Appl Microbiol Biotechnol 1999, 52:741-755.
- [7]Farrell AE, Plevin RJ, Turner BT, Jones AD, O’Hare M, Kammen DM: Ethanol can contribute to energy and environmental goals. Science 2006, 113:506-508.
- [8]Wyman CE: Handbook on Bioethanol: Production and utilization. Wasington: Taylor Francis; 1996.
- [9]Bon EPS, Ferrara MA: Bioethanol production via enzymatic hydrolysis of cellulosic biomass. http://www.fao.org/biotech/docs/bon.pdf webcite
- [10]USDOE: Breaking the biological barriers to cellulosic ethanol: A joint research agenda. In Summary of the Biomass to Biofuels Workshop, held 7–9 December 2005. Rockville, United States; 2006. sponsored by the U.S. Department of Energy
- [11]Hahn-Hagerdal B, Galbe M, Gorwa–Grauslund MF, Liden G, Zacchi G: Bioethanol from-the fuel of tomorrow from residues of today. Trends Biotechnol 2006, 24:549-556.
- [12]Saeman JF: Kinetics of wood saccharification. Ind Eng Chem 1945, 37:43-52.
- [13]Wilke CR, Yang RD, von Stockar U: Preliminary cost analyses for enzymatic hydrolysis of newsprint. Biotechnol Bioeng 1976, 6:155-175.
- [14]Deka D, Jawed M, Goyal A: Purification and characterization of an alkaline cellulase produced by Bacillus subtilis (AS3). Prep Biochem Biotechnol 2013, 43:256-270.
- [15]Duff SJB, Murray WD: Bioconversion of forest products industry waste cellulosics to fuel ethanol: A review. Bioresour Technol 1996, 55:1-33.
- [16]Kumar R, Singh S, Singh OV: Bioconversion of lignocellulosic biomass: Biochemical and molecular perspective. J Ind Microbiol Biotechnol 2008, 35:377-391.
- [17]Sweeney MD, Xu F: Biomass converting enzymes as industrial biocatalysts for fuels and chemicals: Recent developments. Catalysts 2012, 2:244-263.
- [18]Mandels M, Sternberg D: Recent advances in cellulase technology. Ferment Technol 1976, 54:267-286.
- [19]Schulein M: Kinetics of fungal cellulases. Biochem Soc Trans 1998, 26:164-167.
- [20]Wilson DB: Cellulases and biofuels. Curr Opin Biotechnol 2009, 20:295-299.
- [21]Sun Y, Cheng J: Hydrolysis of lignocellulosic materials for ethanol production. Bioresour Technol 2002, 83:1-11.
- [22]Martins LF, Kolling D, Camassola M, Dillon AJ, Ramos LP: Comparison of Penicillium echinulatum and Trichoderma reesei cellulases in relation to their activity against various cellulosic substrates. Bioresour Technol 2008, 99:1417-1424.
- [23]Sharma A, Khare SK, Gupta MN: Hydrolysis of rice hull by crosslinked Aspergillus niger cellulase. Bioresour Technol 2001, 78:281-284.
- [24]Valaskova V, Baldrian P: Degradation of cellulose and hemicelluloses by the brown rot fungus Piptoporus betulinus production of extracellular enzymes and characterization of the major cellulases. Microbiology 2006, 152:3613-3619.
- [25]Kato S, Haruta S, Cui ZJ, Ishii M, Igarashi Y: Stable coexistence of five bacterial strains as a cellulose-degrading community. Appl Environ Microbiol 2005, 71:7099-7106.
- [26]Kaur G, Kumar S, Satyanarayana T: Production, characterization and application of a thermostable polygalacturonase of a thermophilic mould Sporotrichum thermophile Apinis. Bioresour Technol 2004, 94:239-243.
- [27]Banerjee G, Scott-Craig JS, Walton JD: Improving enzymes for biomass conversion: A basic research perspective. Bioenerg Res 2010, 3:82-92.
- [28]Maki M, Leung KT, Qin W: The prospects of cellulase-producing bacteria for the bioconversion of lignocellulosic biomass. Int J Biol Sci 2009, 5(5):500-516.
- [29]Bisaria VS: Bioprocessing of agro-residues to glucose and chemicals. In Bioconversion of Waste Materials to Industrial Products. Edited by Martin AM. London: Elsevier; 1991:210-213.
- [30]Taylor LE, Henrissat B, Coutinho PM, Ekborg NA, Hutcheson SW, Weiner RM: Complete cellulase system in the marine bacterium Saccharophagus degradans strain 2-40T. J Bacteriol 2006, 188:3849-3861.
- [31]Weber S, Stubner S, Conrad R: Bacterial populations colonizing and degrading rice straw in anoxic paddy soil. Appl Environ Microbiol 2001, 67:1318-1327.
- [32]Das SP, Ravindran R, Ahmed S, Das D, Goyal D, Fontes CMGA, Goyal A: Bioethanol production involving recombinant C. thermocellum hydrolytic hemicellulase and fermentative microbes. Appl Biochem Biotechnol 2012, 167:1475-1488.
- [33]Lynd LR, Weimer PJ, van Zyl WH, Pretorius IS: Microbial Cellulose Utilization: Fundamentals and biotechnology. Microbiol Mol Biol Rev 2002, 66(3):506-577.
- [34]Lee J: Biological conversion of lignocellulosic biomass to ethanol. J Biotechnol 1997, 56:1-24.
- [35]Zeng G, Yu H, Huang H, Xi X, Wang R, Huang D, Huang Li G: Microbial community succession and lignocellulose degradation during agricultural waste composting. Biodegradation 2007, 18:793-802.
- [36]Remond C, Aubry N, Cronier D, Noel S, Martel F, Roge B, Rakotoarivonina H, Debeire P, Chabbert B: Combination of ammonia and xylanase pretreatments: Impact on enzymatic xylan and cellulose recovery from wheat straw. Bioresour Technol 2010, 101:6712-6717.
- [37]Kumar R, Wyman CE: Effects of xylanase supplementation of cellulase on digestion of corn stover solids prepared by leading pretreatment technologies. Bioresour Technol 2009, 100:4203-4213.
- [38]Lynd LR, Laser MS, Bransby D, Dale BE, Davidson B, Hamilton R, Himmel ME, Keller M, McMillan JD, Sheehan J: How biotech can transform biofuels. Nat Biotechnol 2008, 26:169-172.
- [39]McMillan JD, Jenning EW, Mohagheghi A, Zuccarello M: Comparative performance of precommercial cellulases hydrolyzing pretreated corn stover. Biotech Biofuels 2011, 4:29.
- [40]Horn SJ, Vaaje-Kolstad G, Westereng B, Eijsink VGH: Novel enzymes for the degradation of cellulose. Biotechnol Biofuels 2012, 5:45. doi:10.1186/1754-6834-5-45
- [41]Scott BR, Hill C, Tomashek J, Liu C: Enzymatic hydrolysis of lignocellulosic feedstocks using accessory enzymes. United States Patent Application 2009/0061484, 5 Mar 2009; 2009.
- [42]Morais S, Barak Y, Caspi J, Hadar Y, Lamed R, Shoham Y, Wilson DB, Bayer EA: Cellulase-xylanase synergy in designer cellulosomes for enhanced degradation of a complex cellulosic substrate. mBio 2010, 1:e00285-00210.
- [43]King BC, Waxman KD, Nenni NV, Walker LP, Bergstrom GC, Gibson DM: Arsenal of plant cell wall degrading enzymes reflects host preference among plant pathogenic fungi. Biotechnol Biofuels 2011, 4:4.
- [44]Zhang P, Himmel ME, Mielenz JR: Outlook for cellulase improvement: Screening and selection strategies. Biotechnol Adv 2006, 24(5):452-481.
- [45]Buthe A: Improving on nature’s enzymes: Transforming nature’s enzymes into the perfect industry catalysts requires a combination of ‘time lapse evolution’ and expert protein engineering. In Chemistry and Industry. Ten Alps Publishing, March 7, 2011; 2011. http://www.highbeam.com/doc/1G1-251855551.html webcite
- [46]Huang JW, Cheng YS, Ko TP, Lin CY, Lai HL, Chen CC, Ma Y, Zheng Y, Huang CH, Zou P, Liu JR, Guo RT: Rational design to improve thermostability and specific activity of the truncated Fibrobacter succinogenes 1,3-1,4-β-D-glucanase. Appl Microbiol Biotechnol 2012, 94(1):111-121.
- [47]Wogulis M, Bohan DM, Osborn D, Benyamino R: Rational design of CBH IIs and BGs for improved activity and thermostability. http://sim.confex.com/sim/34th/webprogram/Paper21296.html webcite
- [48]Liang C, Fioroni M, Rodríguez-Ropero F, Xue Y, Schwaneberg U, Ma Y: Directed evolution of a thermophilic endoglucanase (Cel5A) into highly active Cel5A variants with an expanded temperature profile. J Biotechnol 2011, 154(1):46-53.
- [49]Kubicek CP: The Plant Biomass, in Fungi and Lignocellulosic Biomass. Oxford, UK: Wiley-Blackwell; 2012. 10.1002/9781118414514.ch
- [50]Turner NJ: Directed evolution of enzymes for applied biocatalysis. Trends Biotechnol 2003, 21(11):474-478.
- [51]Song JM, Wei DZ: Production and characterization of cellulases and xylanases of Cellulomicrobium cellulans grown in pretreated and extracted bagasse and mineral nutrient medium M9. Biomass Bioenerg 2010, 34:1930-1934.
- [52]Lehmann C, Sibilla F, Maugeri Z, Streit WR, de María PD, Martinez Z, Schwaneberg U: Reengineering CelA2 cellulase for hydrolysis in aqueous solutions of deep eutectic solvents and concentrated sea water. Green Chem 2012, 14:2719-2726.
- [53]Moraϊs S, Barak Y, Lamed R, Wilson DB, Xu Q, Himmel ME, Bayer EA: Paradigmatic status of an endo- and exoglucanases and its effect on crystalline cellulose degradation. Biotech Biofuels 2012, 5:78.
- [54]Himmel M, Xu Q, Luo Y, Ding S, Lamed R, Bayer E: Microbial enzyme systems for biomass conversion: Emerging paradigms. Biofuels 2010, 1:323-341.
- [55]Alper H, Stephanopoulous G: Engineering for Biofuel: Exploiting innate microbial capacity or importing biosynthetic potential? Nat Rev Microbiol 2009, 7:715-723.
- [56]Gibson DM, King BC, Hayes ML, Bergstrom GC: Plant pathogens as a source of diverse enzymes for lignocellulose digestion. Curr Opinion Microbiol 2011, 14:264-270.
- [57]Sakon J, Irwin D, Wilson DB, Karplus PA: Structure and mechanism of endo/exocellulase E4 from Thermomonospora fusca. Nat Struct Biol 1997, 4(10):810-818.
- [58]Arora A, Nain L, Gupta JK: Solid-state fermentation of wood residues by Streptomyces griseus B1, a soil isolate, and solubilisation of lignins. World J Microbiol Biotechnol 2005, 21:303-308.
- [59]Jang HD, Chen KS: Production and characterization of thermostable cellulases from Streptomyces transformant T3-1. World J Microbiol Biotechnol 2003, 19:263-268.
- [60]Juge N, Svensson B: Proteinaceous inhibitors of carbohydrate-active enzymes in cereals: Implication in agriculture, cereal processing and nutrition. J Sci Food Agric 2006, 86:1573-1586.
- [61]Ortega J: Cell wall degrading enzyme produced by phytopathogenic fungus Colletotrichum gloesporiodes. Texas J Sci 1994, 228:1-6.
- [62]Moreira FG, dos Reis S, Costa MAF, de Souza CGM: Production of hydrolytic enzymes by the plant pathogenic fungus Myrothecium verrucaria in submerged condition. Braz J Microbiol 2005, 36:7-1.
- [63]Chapon V, Czjzek M, El Hassouni M, Py B, Juy M, Barras F: Type II protein secretion in Gram-negative pathogenic bacteria: The study of the structure/secretion relationships of the cellulase Cel5 (formerly EGZ) from Erwinia chrysanthemi. J Mol Biol 2001, 310:1055-1066.
- [64]Barras F, van Gijsegem F, Chatterjee AK: Extracellular enzymes and pathogenesis of soft-rot Erwinia. Annual Rev Phytopathol 1994, 32:201-234.
- [65]Goodwin PH, Sopher CR, Michaels TE: Multiplication of Xanthomonas campestris pv. phaseoli and intercellular enzyme activities in resistant and susceptible beans. J Phytopathol 1995, 143:11-15.
- [66]Huang X, Zhai J, Luo Y, Rudolph K: Identification of a highly virulent strain of Xanthomonas axonopodis pv. malvacearum. Eur J Plant Pathol 2008, 122:461-469.
PDF