Influence of astaxanthin, emulsifier and organic phase concentration on physicochemical properties of astaxanthin nanodispersions

Chemistry Central Journal

Navideh Anarjan²  Imededdine Arbi Nehdi³  Chin Ping Tan¹ 

[1] Department of Food Technology, Faculty of Food Science and Technology, Universiti Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia

[2] Department of Engineering, East Azarbaijan Science and Research Branch, Islamic Azad University, Tabriz, Iran

[3] College of Science, Chemistry Department, King Saud University, Riyadh 1145, Saudi Arabia

关键词: Emulsion component;    Nanodispersion;    Emulsification-evaporation;    Astaxanthin;   

Others  :  787866
DOI  :  10.1186/1752-153X-7-127

 received in 2013-05-01, accepted in 2013-07-15,  发布年份 2013

【 摘 要 】

Background

The emulsification-evaporation method was used to prepare astaxanthin nanodispersions using a three-component emulsifier system composed of Tween 20, sodium caseinate and gum Arabic. Using Response-surface methodology (RSM), we studied the main and interaction effects of the major emulsion components, namely, astaxanthin concentration (0.02–0.38 wt %, x₁), emulsifier concentration (0.2–3.8 wt %, x₂) and organic phase (dichloromethane) concentration (2–38 wt %, x₃) on nanodispersion characteristics. The physicochemical properties considered as response variables were: average particle size (Y₁), PDI (Y₂) and astaxanthin loss (Y₃).

Results

The results indicated that the response-surface models were significantly (p < 0.05) fitted for all studied response variables. The fitted polynomial regression models for the prediction of variations in the response variables showed high coefficients of determination (R² > 0.930) for all responses. The overall optimum region resulted in a desirable astaxanthin nanodispersions obtained with the concentrations of 0.08 wt % astaxanthin, 2.5 wt % emulsifier and 11.5 wt % organic phase.

Conclusion

No significant differences were found between the experimental and predicted values, thus certifying the adequacy of the Response-surface models developed for describing the changes in physicochemical properties as a function of main emulsion component concentrations.

【 授权许可】

   
2013 Anarjan et al.; licensee Chemistry Central Ltd.

【 图 表 】

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