Development of an ultra low noise, miniature signal conditioning device for vestibular evoked response recordings

BioMedical Engineering OnLine

Chathura L Kumaragamage²  Brian J Lithgow¹  Zahra Moussavi¹ 

[1] Riverview Health Centre, Winnipeg, Manitoba, Canada

[2] The Department of Electrical and Computer Engineering, University of Manitoba, Winnipeg, Canada

关键词: Ultra-low noise;    Right leg driver;    RFI filtering;    Power line interference;    Parallel amplifier;    Electrovestibulography;    Electrocochleography;    Bio-signal amplifier;    Active shielding;   

Others  :  797212
DOI  :  10.1186/1475-925X-13-6

 received in 2013-09-24, accepted in 2014-01-09,  发布年份 2014

【 摘 要 】

Background

Inner ear evoked potentials are small amplitude (<1 μV_pk) signals that require a low noise signal acquisition protocol for successful extraction; an existing such technique is Electrocochleography (ECOG). A novel variant of ECOG called Electrovestibulography (EVestG) is currently investigated by our group, which captures vestibular responses to a whole body tilt. The objective is to design and implement a bio-signal amplifier optimized for ECOG and EVestG, which will be superior in noise performance compared to low noise, general purpose devices available commercially.

Method

A high gain configuration is required (>85 dB) for such small signal recordings; thus, background power line interference (PLI) can have adverse effects. Active electrode shielding and driven-right-leg circuitry optimized for EVestG/ECOG recordings were investigated for PLI suppression. A parallel pre-amplifier design approach was investigated to realize low voltage, and current noise figures for the bio-signal amplifier.

Results

In comparison to the currently used device, PLI is significantly suppressed by the designed prototype (by >20 dB in specific test scenarios), and the prototype amplifier generated noise was measured to be 4.8

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【 授权许可】

   
2014 Kumaragamage et al.; licensee BioMed Central Ltd.

【 图 表 】

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