Endoglucanases: insights into thermostability for biofuel applications

Biotechnology for Biofuels

Ragothaman M Yennamalli²  Andrew J Rader¹  Adam J Kenny⁴  Jeffrey D Wolt⁵  Taner Z Sen³ 

[1] Present Address: State Farm Insurance, Indianapolis 46240, IN, USA

[2] Present Address: Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, USA

[3] 1025 Crop Genome Informatics Lab, Iowa State University, Ames 50011, IA, USA

[4] Present Address: Brownells, Inc, Montezuma, IA 50171, USA

[5] Biosafety Institute for Genetically Modified Agricultural Products and Department of Agronomy, Iowa State University, Ames 50011, IA,USA

关键词: Mutant;    Cellulases;    Thermostability;    Endoglucanase;    Biofuel;   

Others  :  797895
DOI  :  10.1186/1754-6834-6-136

 received in 2013-06-04, accepted in 2013-09-24,  发布年份 2013

【 摘 要 】

Obtaining bioethanol from cellulosic biomass involves numerous steps, among which the enzymatic conversion of the polymer to individual sugar units has been a main focus of the biotechnology industry. Among the cellulases that break down the polymeric cellulose are endoglucanases that act synergistically for subsequent hydrolytic reactions. The endoglucanases that have garnered relatively more attention are those that can withstand high temperatures, i.e., are thermostable. Although our understanding of thermostability in endoglucanases is incomplete, some molecular features that are responsible for increased thermostability have been recently identified. This review focuses on the investigations of endoglucanases and their implications for biofuel applications.

【 授权许可】

   
2013 Yennamalli et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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