Preliminary study for non – invasive optical detection of squamous and basal cell carcinomas

BioMedical Engineering OnLine

Ahmed Mohammed Ali²  Munqith Saleem Dawood²  Mohammed Kadhim Taher¹  Faeza Aftan Zghair² 

[1] College of Medicine, Dermatology Department, Babylon university, Babylon, Iraq

[2] College of Engineering, Medical Engineering Department, Al-Nahrain University, Baghdad, Iraq

关键词: Reflectometry;    Oblique incidence diffuse reflectance;    Diffusion theory;    Skin cancer detection;   

Others  :  797979
DOI  :  10.1186/1475-925X-11-88

 received in 2012-06-29, accepted in 2012-11-13,  发布年份 2012

【 摘 要 】

Background

The early detection of skin cancer may highly increase the chances of its healing. One of the non-invasive methods of such detection based on the Oblique- Incidence Diffuse Reflectance (OIDR) measurements of the reflected diode laser light from the skin. In this research we designed and implemented the OIDR reflectometry measuring system with a 650 nm diode laser source to aid physicians in diagnosing both squamous cell carcinomas (SCC) and basal cell carcinomas(BCC).

Method

The laser is delivered obliquely to the skin surface by an optical fiber fitted through a tube holder of CCD camera. The diffused reflected laser light from the skin is captured by the CCD camera and sent to a computer, which is supplied by a specially prepared Matlab program to analyze these images in order to decide in a time whether the lesion is malignant or benign. Fifty cases were diagnosed under supervision of the consultant section of The Governmental Specialized Marjan Teaching Hospital – MOH – Iraq.

Result

The fifty diagnosed cases by this technique, the results were 90% accurate.

Conclusion

The method of laser oblique-incidence diffuse reflectance (OIDR) combined with using the developed algorithms that have high classification rates may prove useful in the clinic as the process is fast, noninvasive and accurate.

【 授权许可】

   
2012 Mohammed et al.; licensee BioMed Central Ltd.

【 图 表 】

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