开放课件详细信息
Directed Evolution: Engineering Biocatalysts | |
8 Enzyme evolution using phage display (cont.) Affinity selection for improved catalysts has limitations; not all enzymatic activities have suitable suicide substrates. Direct selection of enzymes on the basis of catalysis is possible using phage display technology, but is more complex as a physical link between the phage-bound enzyme and the substrate must be established. We will discuss how this type of selection is achieved using two different examples of substrate linkage Notes | |
Life Sciences Courses;Biological Engineering--Biomaterials;Biology--Cell Biology;Biology--Genetics | |
授课人:Dr. Kerry Love | |
机构:Massachusetts Institute of Technology | |
主题词:58.1 | |
美国|英语 | |
【 授权许可】
CC BY-NC-SA
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
8 Enzyme evolution using phage display (cont.) Affinity selection for improved catalysts has limitations; not all enzymatic activities have suitable suicide substrates. Direct selection of enzymes on the basis of catalysis is possible using phage display technology, but is more complex as a physical link between the phage-bound enzyme and the substrate must be established. We will discuss how this type of selection is achieved using two different examples of substrate linkage Notes | 89KB | download | |
8 Enzyme evolution using phage display (cont.) Affinity selection for improved catalysts has limitations; not all enzymatic activities have suitable suicide substrates. Direct selection of enzymes on the basis of catalysis is possible using phage display technology, but is more complex as a physical link between the phage-bound enzyme and the substrate must be established. We will discuss how this type of selection is achieved using two different examples of substrate linkage Notes | 230KB | download |