Characterization of sunscreen cream containing benzophenone-3,3',4,4'-tetracarboxylate dianhydride

3rd Annual Applied Science and Engineering Conference

工业技术;自然科学

Djalil, A.D.^1 ; Ambarwati, T.^1 ; Genatrika, E.^1

Faculty of Pharmacy, Universitas Muhammadiyah Purwokerto, Jl. Raya Dukuhwaluh PO. Box 202, Purwokerto

53182, Indonesia^1

关键词: Adhesivity;    Adverse effect;    Benzophenone-3;    Physical characteristics;    Spreadability;    Sun protection;    Sun protection factor;    Ultra-violet;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/434/1/012090/pdf
DOI  :  10.1088/1757-899X/434/1/012090

来源: IOP

【 摘 要 】

The purpose of this research was to evaluate in-vitro sunscreen activity of a cream formulation containing benzophenone-3,3',4,4'-tetracarboxylate dianhydride (BTDA). Sunscreen is used to protect skin from the adverse effects of ultraviolet (UV)A (320-400 nm) and UVB (290-320 nm) radiation. The most common chemical sunscreen is derivatives of benzophenone. The potency of benzophenone-3,3',4,4'-tetracarboxylate dianhydride for sun protection was evaluated using in-vitro spectrophotometric technique. Several cream formulation containing 5% (F1), 6% (F2), and 7% (F3) BTDA were designed. These cream were subjected to physical characteristic such as, organoleptic, viscosity, homogeneity, pH, spreadability, adhesivity, and stability (tuliskan satuan -bila ada). The sun protection factors (SPF) were analyzed by spectrophotometry using samples irradiated with UV in B region. All cream formulations showed good physical characteristics. The formulation of sunscreen cream containing BTDA meets the requirements of physical properties. SPF values of BTDA, F1, F2, and F3 were 6.40±0.21; 0.27±0.03; 0.87±0.01; and 0.56±0.00, respectively. All cream formulations of sunscreen cream containing BTDA meets the requirements of physical properties with satisfactory characteristics, but does not indicate any sun protection activities.