Hydrogel film of polyethylene oxide-polypropylene glycol diacrylate for wound dressing application

2017 1st International Conference on Engineering and Applied Technology

Haryanto^1 ; Aini, A.N.^1

Chemical Engineering Department, Faculty of Engineering, Universitas Muhammadiyah Purwokerto, Indonesia^1

关键词: Electron beam irradiation;    High mechanical strength;    Hydrogel polymers;    Optimum composition;    Polyethylene oxide (PEO);    Polypropylene glycol;    Swelling capacities;    Water vapor transmission rate;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/403/1/012014/pdf
DOI  :  10.1088/1757-899X/403/1/012014

来源: IOP

【 摘 要 】

Hydrogel polymer receives more attention in medical and other applications due to its biocompatibility properties and swelling ratio. Hydrogel has an ability to absorb and retain water, a property which is very useful for medical applications. We developed polyethylene oxide (PEO)-polypropylene glycol diacrylate (PPGDA) hydrogel film through electron beam irradiation for wound dressing application. Various compositions of PPGDA/PEO (0%, 5%, 10%, 15% and 20%) were irradiated using electron beam to obtain the optimum composition for a better hydrogel characteristic. The PPGDA content in the hydrogel film influences the level of swelling capacity, gel fraction and mechanical strength. The results show that 20% PPGDA content of hydrogel film has the highest mechanical strength (6,2 N/mm2). The composition of 20% PPGDA hydrogel film also has the highest gel fraction (79%). However, the hydrogel prepared using that composition has the lowest swelling ratio (300%). Based on the results, 20% PPGDA hydrogel film is very potential for wound dressing application with high mechanical strength and ideal water vapor transmission rate.