Research and Preliminary Evaluation on Inclusion Preparation of volatile oil in Toona sinensis fruit and β-CD

2018 5th International Conference on Advanced Composite Materials and Manufacturing Engineering

Li, Wanzhong^1 ; Zhu, Zefeng^1 ; Lu, Yan^1

Pharmacy College, Weifang Medical University, 7166 West Baotong Street, Weifang City, China^1

关键词: Development and applications;    Evaluation index;    Inclusion compounds;    Inclusion rate;    Orthogonal method;    Theoretical foundations;    Toona Sinensis;    Water addition;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/394/2/022051/pdf
DOI  :  10.1088/1757-899X/394/2/022051

来源: IOP

【 摘 要 】

The grinding-based inclusion preparation of volatile oil in Toona sinensis fruit and β-CD was optimized and the prepared inclusion compound was evaluated preliminary. Methods: The yield rate of inclusion compound and inclusion rate were used as evaluation indexes to investigate rate of charge, water addition and grinding time. The inclusion preparation of volatile oil β-CD was optimized through the orthogonal method. Inclusion compound was assessed by TLC method and microscope. Results: The optimized grinding technique is: 1:8 of mixing rate of volatile oil and β-CD, 4 times of water addition and 60min grinding. TLC method and microscope prove that composition of volatile oil in Toona sinensis fruit remains same before and after the inclusion. It is included by β-CD. Conclusions: The proposed grinding technique is simple in operation, reasonable and feasible. It can lay theoretical foundation for the development and application of volatile oil in Toona sinensis fruit.