Studies on the acid degradation process and in vitro immune activity of the polysaccharide H6PC20 in Hericium erinaceus

International Conference on Manufacturing Technology, Materials and Chemical Engineering

机械制造;材料科学;化学工业

Li, Tingting^1,2 ; Li, Caijin^2,3 ; Wu, Di^1 ; Yang, Yan^2 ; Jin, Yueling^1

Institute of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai

2001318, China^1

Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai

201403, China^2

College of Life and Environmental Science, Shanghai Normal University, Shanghai

200234, China^3

关键词: Acid concentrations;    Acid degradation;    Acid treatments;    Degradation time;    Hericium erinaceus;    Immune activity;    Removal capacity;    Sulfuric acid and hydrochloric acid;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/392/5/052014/pdf
DOI  :  10.1088/1757-899X/392/5/052014

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

In this paper, the degradation and modification of the macromolecule polysaccharide (H6PC20) extracted from Hericium erinaceus was carried out by acid treatment, and a set of Hericium erinaceus polysaccharides with proper molecular weight were obtained to improve the biological activities of H6PC20. The effects of citric acid, trifluoroacetic acid, sulfuric acid and hydrochloric acid on the degradation of polysaccharide H6PC20 were compared, and it was found that trifluoroacetic acid was most suitable for degrading the polysaccharide in Hericium erinaceus. With the increasing of the degradation time, the proportion of polysaccharides with large molecular weight reduced, and the in vitro immune activity decreased, and the DPPH removal capacity increased gradually. With the increasing of trifluoroacetic acid concentration, the molecular weights of the degraded polysaccharides decreased, and the proportion of polysaccharides with large molecular weight reduced. When the acid concentration was 0.1∼0.5 M and the molecular weight was 1.57∼1.97×106 Da, the immune activities of the degraded polysaccharides markedly enhanced and the DPPH removal rate increased gradually compared with both before the degradation of H6PC20.