Quantitative analysis of lignans in Ginseng Schisandra Granules by HPLC

International Conference on Manufacturing Technology, Materials and Chemical Engineering

机械制造;材料科学;化学工业

Bai, Jing^1,2 ; Zhang, Caiyun^1,2

Research Center of Life Scineces and Environmental Sciences, Harbin University of Commerce, Harbin

150076, China^1

Research Center of Nature Drug Engineering for Anti-tumor, Ministry of Education, Harbin

150076, China^2

关键词: Analytical method;    Kromasil C18;    Linear range;    Mobile phase;    Quantitative determinations;    Schisandra;    Schizandrol a;    UV detection;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/392/5/052002/pdf
DOI  :  10.1088/1757-899X/392/5/052002

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

A simple and rapid analytical method for the quantitative determination of two lignans of Ginseng Schisandra Granules was developed. The determination was carried out on a Kromasil C18 column (250 mm×4.6 mm, 5 μm)with mobile phase of acetonitrile-water(52:48). UV detection was performed at 218 nm, flow rate was 0.8 ml/min. The linear range of schizandrol A and schizandrol B were 16.03∼160.3 μg/mL, 5.26∼52.6 μg/mL, the mean recovery were 98.9%, 98.1%. The method is suitable for the quality control of Ginseng Schisandra Granules.