Preliminary application of cerium-based hollow nanospheres as drug carrier

6th International Conference on Nanomaterials and Materials Engineering

Li, J.C.^1,2,3 ; Jiang, H.^1,2,3 ; Wang, X.M.^1,2,3

School of Biological Science and Medical Engineering, Southeast University, Nanjing

210096, China^1

State Key Lab of Bioelectronics (Chien-Shiung Wu Laboratory), Southeast University, No. 2 Sipailou, Nanjing

210096, China^2

National Demonstration Center for Experimental Biomedical Engineering Education, Southeast University, Nanjing

210096, China^3

关键词: Biological fields;    Cardio-vascular disease;    Chemical activities;    Glass additive;    Hollow nanospheres;    Radiation-induced;    Scope of application;    Tissue damage;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/380/1/012017/pdf
DOI  :  10.1088/1757-899X/380/1/012017

来源: IOP

【 摘 要 】

As more and more chemical activity and biological activity are found, cerium, one of the largest reserves of cheap rare earth lanthanides, is widely used in many fields such as flint, decolorizer, abrasive polish, glass additives, reducing agents, catalysts, harmful metal substitutes and other special functional materials. Cerium nanoparticles can be used in cardiovascular diseases, neurodegenerative diseases and radiation-induced tissue damage, also be used as biomimetic enzymes, biocatalysis, biomedicine, biological scaffolding and other biological fields. However, cerium-based hollow nanospheres have never been properly tested as a drug carrier. In this report, we explored the potential of cerium-based materials as a drug carrier which is a brand new attempt to expand the scope of application of cerium-based nanomaterials in the field of biomedicine.